6 Best Ketoconazole Shampoos Of 2021 For An Itch-Free Scalp

Written by Shreya Vishwanathan
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Those who experience hair fall, dandruff, and buildup try countless hair products and still find themselves coming right back to square one, despite promising short-term results. If you relate to this and find yourself trying every type of product and home remedy that claims to help, you might as well consider using a ketoconazole shampoo for good reasons. Most medicated shampoos contain ketoconazole, and this dermatologist-recommended ingredient works to buff away dandruff and promote thicker, longer hair.

If you’re not willing to travel that route and try medicated shampoos, worry not. Ketoconazole is also used in many OTC shampoos, and we’re here to your rescue with our list of the best ketoconazole shampoos that don’t require a prescription but are just as effective. As a bonus, these shampoos have a wealth of other hair-loving ingredients that will make you fall in love with these shampoos. Without any further ado, let’s dive right in.

6 Best Ketoconazole Shampoos – Say Goodbye To Flakes

Top 6 ProductsCheck Price
Nizoral A-D Ketoconazole Anti-Dandruff Shampoo 1%Check Price
Regenepure dr Hair And Scalp TreatmentCheck Price
Pura d’or M.D. Maximum Defense Anti-Hair Thinning ShampooCheck Price
Hair Restoration Laboratories Professional Strength Hair Restore ShampooCheck Price
Wick & Strom Hair Revitalizing Caffeine Infused ShampooCheck Price
Sent From: Earth Caffeine & Saw Palmetto Biotin Ketoconazole ShampooCheck Price

1. Nizoral A-D Ketoconazole Anti-Dandruff Shampoo 1%

Dandruff, an itchy scalp, and flakiness are all the outcomes of dermatitis. If you’re on the lookout for an OTC ketoconazole 1% shampoo, look no further. The Nizoral ketoconazole shampoo is an effective and potent formula that fights dandruff outbreaks. The shampoo works like magic, even for color-treated hair without stripping the hair of color. It is a gentle formula, and if you’re wondering how frequently you should use it, twice a week will fetch you optimal results.


  • Gentle formula
  • Relieves itchiness
  • Lathers well
  • Suitable color-treated hair


  • Contains artificial fragrance

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2. Regenepure dr Hair And Scalp Treatment

The most immediate outcome of developing dandruff is hair fall. Try this hair loss ketoconazole shampoo to fight buildup for hair loss prevention and effective dandruff treatment. It gets rid of any debris and DHT on the scalp and deeply cleanses, so your follicles get the nourishment they need to promote healthy hair growth. While some of the key ingredients are salicylic acid and ketoconazole, it is also infused with nourishing elements like jojoba oil, emu oil, niacin, vitamin B3 and B6, and aloe vera. Give this shampoo containing ketoconazole a shot if you prefer chemical-free hair care products.


  • Combats hair loss
  • Hydrates
  • Free of harsh chemicals
  • Sulfate and paraben-free


  • May not add volume to hair

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3. Pura d’or M.D. Maximum Defense Anti-Hair Thinning Shampoo

If your hair falls prey to thinning and you also face dandruff problems, you need a chemical-free, enriching anti-dandruff ketoconazole shampoo for thinning hair like this one. It is the perfect combination of science and nature as it blesses your hair follicles with a blend of oils, green tea leaf extract, vitamin E, and 0.5% coal tar for a clean and healthy scalp. It also helps lock in moisture, so that you don’t have frizzy hair soon after washing your hair. Couple your regular shampoo with this and you’ll witness an extraordinary hair transformation.


  • Fights dryness in the scalp
  • Hypoallergenic
  • Non-GMO ingredients
  • Free of harmful chemicals
  • Cruelty-free


  • May not be suitable for extreme buildup

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4. Hair Restoration Laboratories Professional Strength Hair Restore Shampoo

This is yet another thoughtfully formulated dandruff shampoo with ketoconazole that boasts a long, impressive list of natural ingredients. Haircare products from Hair Restoration Laboratories, including this one, are popular for containing 25% more DHT blockers. DHT is a hormone that causes hair loss. This shampoo is a blend of caffeine, aloe vera, ginger extract, hops extract, vitamin E, pea extract, lemon oil, white nettle extract, cayenne pepper extract among many other ingredients that enrich your hair strands right from the roots to the tips. Invest in this OTC ketoconazole shampoo for a clean scalp and longer, stronger, and thicker hair.


  • Blocks DHT
  • Thickens hair
  • Reverses hair loss
  • Free of sulfates and parabens
  • Silicone-free


  • May not be as hydrating as expected

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5. Wick & Strom Hair Revitalizing Caffeine Infused Shampoo

If you’re a fan of tropical scents, make the most out of this shampoo with ketoconazole with pleasant notes of mango. It gives your hair follicles a good wash while nourishing them with a blend of vitamins, aloe vera juice, hops extract, mango seed butter, among other natural elements. It also stimulates the follicles to promote hair growth. To add to the host of benefits, the shampoo contains biotin that gives your hair the strength and resilience it needs to be healthy and look supple.


  • Prevents hair loss
  • Invigorating formula
  • Promotes hair growth
  • Suitable for all hair types


  • Contains sulfates

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6. Sent From: Earth Caffeine & Saw Palmetto Biotin Ketoconazole Shampoo

This vegan ketoconazole shampoo from Sent From Earth is worth the splurge if hair fall prevention is at the top of your hair goals. It is a fusion of ingredients that consists of caffeine, saw palmetto, ketoconazole, biotin, and organic oils that clean the hair follicles and scalp to stimulate hair growth. This over-the-counter ketoconazole shampoo is formulated without sulfates, parabens, synthetic fragrances, phthalates, and formaldehydes, which gives us more reasons to depend on it without worrying about harsh chemicals weakening our hair in the long run.


  • Promotes hair regrowth
  • Prevents hair breakage
  • Nourishes
  • Natural formula
  • Clinically-tested


  • Slightly expensive

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We’ve put all the efforts to cover the best ketoconazole shampoos that are available on the market currently. However, there’s so much more to a shampoo that you need to consider to make the right decision. We’re here to your rescue with our buying guide.

How To Choose The Best Ketoconazole Shampoo?

  • Ketoconazole concentration

Most over-the-counter, generic ketoconazole shampoos that are as effective as medicated ketoconazole shampoos generally contain 2% ketoconazole. This can be very beneficial for those who have a severe case of buildup and hair fall. However, you can only use a high concentration ketoconazole shampoo once a week. However, shampoos with lower concentration can be used almost daily.

  • Hair type

Some of the ketoconazole shampoos may cause dryness. If you have dry hair, you can look for a shampoo that has essential oils, aloe vera, or other hydrating ingredients. For oily hair, it is best to avoid shampoos that contain oils. You can check the product label to see if the shampoo suits your hair type. Make it a point to specifically check if or not the shampoo is suitable for color-treated or chemically processed hair if you have colored or treated your hair.

  • Additional ingredients

While ketoconazole in itself is quite effective at tackling hair fall, a few other ketoconazole shampoo ingredients such as biotin, caffeine, and saw palmetto blocks, and herbal extracts can improve the results for your hair fall problem.

  • Additional benefits

Using ketoconazole shampoo for hair fall shouldn’t mean that you forget about other hair problems. If you’re dealing with other issues like thinning and dandruff flakes or just want your shampoo to work its wonders to stimulate hair growth, you can look for additional ingredients like tea tree oil, almond oil, green tea extract, chamomile extract, etc. that delivers a positive outcome for overall healthy hair.

Are you confused about how to use a shampoo with ketoconazole? Here’s a segment that will help you understand how to use ketoconazole shampoo.

How To Use Ketoconazole Shampoo?

  • Step 1: Wet your hair
  • Step 2: Pour some ketoconazole shampoo of your choice on your palm according to your hair length and volume and massage your scalp with it, evenly spreading it across the length of your hair.
  • Step 3: Once it lathers well, rinses the shampoo off and follow it up with a conditioner of your choice.

If you’re wondering what are the many benefits of using ketoconazole shampoo, here are the several ways in which it can transform your hair to be healthy.

Benefits Of Ketoconazole Shampoo

  • Ketoconazole helps rid the scalp of fungi and other microbes that lead to buildup and chronic dandruff with its antifungal and antimicrobial properties.
  • It remediates dryness and flakiness.
  • It promotes hair growth.
  • It prevents hair loss.

Finding the right ketoconazole shampoo can be an ordeal. But we hope that our list of the 6 best ketoconazole shampoos and our comprehensive buying guide gives you enough options to weigh the pros and cons and settle for one that does justice to your hair. Ketoconazole can be a blessing in a shampoo bottle if you witness increased hair fall, buildup, and hair thinning. Depending on the concentration of ketoconazole in your shampoo, it can take anywhere between 2 weeks to 2 months for you to witness results. However, we can assure you that the outcomes will be worth the wait.

Frequently Asked Questions

Does ketoconazole shampoo cause hair loss?

No, on the contrary, ketoconazole shampoos are used to remediate hair loss and to promote hair growth. If you’re witnessing hair loss from a ketoconazole shampoo, it could be other ingredients causing this problem.

Does ketoconazole shampoo have side effects?

Some of the rare side effects caused by ketoconazole shampoo are itching, hair discoloration, burning sensation, contact dermatitis, hypersensitivity, etc. This is why it is recommended to do a patch test before you start using the shampoo.

Does ketoconazole shampoo treat dandruff?

Yes, ketoconazole shampoos can treat dandruff and buildup.

Is ketoconazole shampoo safe to use during pregnancy?

It is always recommended to consult a doctor before you use a specific ketoconazole shampoo when you’re pregnant.

Is ketoconazole shampoo good for acne?

If your facial acne is caused by dandruff and hair buildup, using a ketoconazole shampoo may help reduce your acne by getting rid of the buildup.

How many times a week should I use ketoconazole shampoo?

While higher concentration ketoconazole shampoos should be used once or twice a week, you can use a gentle ketoconazole shampoo like a regular shampoo. You can read the product label to check how many times you can use the shampoo.

Can you use regular shampoo after ketoconazole?

Since ketoconazole shampoo helps clean the scalp and hair pretty much like any regular shampoo, you wouldn’t need to follow up with another shampoo when you use ketoconazole shampoo.

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Shreya is an SEO-content writer and has worked with various organizations to craft unique and creative content. Holding a Master’s degree in Clinical Psychology, she calls herself a lifelong learner driven by curiosity to tap into different fields and the will to push her boundaries. She combines her curiosity and love for writing to write about subjects that are valuable to fashion enthusiasts.