13 Best Niacinamide Serums – Reviews And Guide

by Swathi Handoo
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Niacinamide is a natural anti-inflammatory agent. It is one of the most abundant forms of vitamin B3. Thus, it is an essential nutrient too. Our body obtains niacinamide via our diet and several supplements. However, it is most effective in serum form when dealing with topical inflammation. Niacinamide serums control flare-ups, rosacea, redness, eczema, rashes, and hypersensitivity.

If one or all of these are your current skin concerns, a high-performance niacinamide serum is what you need. But, where to start? Choose from the 13 best niacinamide serums listed in this article. Read till the end to know how to pick the best one out of the lot.

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Best Paraben-Free Serum – InstaNatural Niacinamide Serum
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Best Hydrating Serum – Neutrogena® Hydro Boost Multivitamin Booster
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Tree Of Life Niacinamide Serum
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Naturium Niacinamide Serum 12% Plus Zinc 2%
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Joyal Beauty Vitamin B3 B5 Serum
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Cos De BAHA Niacinamide 10 Serum
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Valjean Labs Restore Niacinamide + Zinc Facial Serum
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Skin Daily Vitamin B3 Niacinamide 5% Serum
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Bliss Glow & Hydrate Niacinamide + Hyaluronic Acid Day Serum
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Best Serum For Mature Skin – QRxLabs Niacinamide + Retinol Serum
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Top 13 Niacinamide Serums Your Skin Will Love

1. Best Paraben-Free Serum – InstaNatural Niacinamide Serum

InstaNatural Niacinamide Serum restores and maintains your skin’s protective barrier. It aids in fighting against external inflammatory factors that cause breakouts, hyperpigmentation, blemishes, and signs of skin aging. This serum has a unique blend of botanical extracts that supplement niacinamide. They include avocado oil, rosemary extract, hyaluronic acid, meadowfoam seed oil, hibiscus extract, lavender oil, and Asian pennywort. It deeply nourishes the skin layers and treats free radical damage. When used regularly, this niacinamide serum tightens skin pores and plumps up sagging skin. It leaves behind a natural radiance and is gentle on all skin types.

Key Ingredients: Hyaluronic acid, niacinamide, avocado oil, rosemary extract, aloe leaf juice, meadowfoam seed oil, and Asian pennywort

Pros

  • Brightens the complexion
  • Deeply nourishing formula
  • Suitable for all skin types
  • Lightens acne scars
  • Relieves redness
  • Lightweight
  • Gentle on sensitive skin
  • Paraben-free
  • No synthetic fragrances
  • Mineral oil-free
  • Preservative-free
  • Pleasant fragrance

Cons

  • May dry out the skin
  • May cause breakouts

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2. Best Hydrating Serum – Neutrogena® Hydro Boost Multivitamin Booster

Neutrogena® Hydro Boost Multivitamin Booster Serum features hyaluronic acid and niacinamide as active ingredients along with other botanicals and biochemical ingredients that energize and brighten dull and pale skin. This serum instantly replenishes and restores the moisture barrier of your skin. It deeply hydrates and soothes dry and irritated skin with a single application. Its weightless and non-comedogenic formula revitalizes and clears up oily and acne-prone skin. You can mix this serum with your regular moisturizer and wear it all day under makeup too.

Key Ingredients: Niacinamide, glycerin, hyaluronic acid, tocopherol, Irish moss powder, river weeds extract, and citric acid

Pros

  • Offers deep hydration
  • Soothes dry and irritated skin
  • Non-comedogenic
  • Dermatologist-tested
  • Mineral oil-free
  • Gets absorbed quickly
  • Non-sticky
  • Spreads well
  • Refreshing scent
  • Leaves no residue
  • Suitable for dry and sensitive skin
  • Can be worn under makeup

Cons

  • Thick gel consistency
  • May cause breakouts

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3. Tree Of Life Niacinamide Serum

Tree Of Life Niacinamide Serum has superior moisturizing and skin-tightening properties. It softens and conditions dry and sensitive skin by preventing moisture loss. This formula dries quickly and can be used under makeup or before going to bed. The natural antioxidants in aloe leaves, neem seeds, rosemary leaves, sunflower seeds, and avocado tighten the skin pores and brighten the complexion. Hyaluronic acid and niacinamide hydrate your skin and stimulate collagen production naturally. Use this serum regularly to get plumper, smoother, and healthier skin with smaller pores.

Key Ingredients: Niacinamide, aloe leaf juice, avocado oil, hyaluronic acid, neem seed oil, sunflower seed oil, and rosemary leaf extract

Pros

  • Tightens the skin
  • Nourishes dry skin
  • Prevents moisture loss
  • Long-lasting
  • Can be worn under makeup
  • Suitable for all skin types
  • Easy to apply
  • Affordable

Cons

  • Thick consistency
  • May clog pores

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4. Naturium Niacinamide Serum 12% Plus Zinc 2%

Naturium Niacinamide Serum is a concentrated product with 12% pure niacinamide and 2% zinc PCA. This high-performance serum lightens uneven skin tone and minimizes the appearance of open pores. It polishes your skin texture by smoothening out fine lines and lightening dark spots. Despite the high concentration of niacinamide (vitamin B3) and zinc salt, this formula is set to a safe pH of 5.0-5.6. This potent combination improves the complexion of inflamed and clogged skin. The Naturium Niacinamide Serum is preservative-free, cruelty-free, and safe to be used on all skin types.

Key Ingredients: Niacinamide, Zinc PCA, sodium hyaluronate, and citric acid

Pros

  • Appropriate pH level
  • Softens fine lines
  • Subtle fragrance
  • Gets absorbed quickly
  • Tightens skin pores
  • Reduces acne and scars
  • Brightens the skin
  • Suitable for all skin types

Cons

  • Thick consistency
  • Difficult to apply

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5. Joyal Beauty Vitamin B3 B5 Serum

This Vitamin B3 and B5 serum by Joyal Beauty contains 5% niacinamide which is a safe and effective concentration for all skin types. It reduces the appearance of the signs of aging such as uneven skin tone, enlarged pores, fine lines, wrinkles, and dark spots. Vitamins B3 and B5 enhance the elasticity of mature and stressed skin. This serum also contains hyaluronic acid – a potent natural hydrating agent.

It replenishes moisture and restores radiance in your skin for a smooth and supple feel. The Zinc PCA Complex controls the excess sebum secretion in acne-prone skin and supports the activity of hyaluronic acid. Since it is lightweight and oil-free, this Joyal Beauty serum works well on all skin types – dry, normal, combination, sensitive, oily, and acne-prone.

Key Ingredients: Vitamins B3 and B5, hyaluronic acid, and zinc PCA

Pros

  • Improves skin elasticity
  • Suitable for all skin types
  • Offers deep hydration
  • Plumps up mature skin
  • Oil-free formula
  • Lightweight
  • Fast-acting formula
  • Reduces oiliness
  • High-quality packaging

Cons

  • May cause breakouts
  • Strong fragrance

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6. Cos De BAHA Niacinamide 10 Serum

The Niacinamide 10 Serum by Cos De BAHA features sun protecting, anti-aging, anti-inflammatory, and hydrating agents. These antioxidant-rich extracts prevent premature skin aging caused by free radicals and UV rays. Soothing components like allantoin, aloe leaf juice, and niacinamide calm eczema, acne, and itching. Niacinamide also boosts the natural collagen production to plump up and blur wrinkles, fine lines, and crepey skin.

This niacinamide product minimizes open pores and tone differences. It is safe for daily use as it has no preservatives, synthetic ingredients, and hydroquinone. This silky serum disappears instantly into the skin. Hence, it can be used under makeup or with other non-acidic skin care products.

Key Ingredients: Aloe leaf juice, allantoin, niacinamide, witch hazel leaf extract, rosemary leaf extract, thyme extract, eucalyptus leaf extract

Pros

  • Non-greasy
  • Fights hyperpigmentation
  • Paraben-free
  • Restores moisture barrier
  • No artificial color
  • Soothes dry skin
  • Minimizes pores
  • Gets absorbed quickly
  • Long-lasting hydration
  • Easy to apply

Cons

  • May cause acne
  • Inconsistent product quality

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7. Valjean Labs Restore Niacinamide + Zinc Facial Serum

Valjean Labs Niacinamide + Zinc Facial Serum contains an active blend of niacinamide and zinc that soothes inflamed skin. It softens blemishes, breakouts, wrinkles, fine lines, redness, and sun damage on all skin types. This serum also contains moisturizing honeysuckle flower extract that deeply nourishes dry and sensitive skin. Zinc naturally enhances collagen production to make your skin look firmer, younger, and lifted. This lightweight serum is non-sticky and controls excess sebum production. It smoothens the skin texture and adds a youthful radiance to it with consistent use.

Key Ingredients: Niacinamide, zinc, and honeysuckle flower extract

Pros

  • Lightweight
  • Non-greasy
  • Suitable for all skin types
  • Soothes acne
  • Reduces wrinkles
  • Minimizes large open pores
  • Easy to apply
  • Gets absorbed quickly
  • Controls oiliness
  • Affordable
  • Long-lasting
  • User-friendly applicator

Cons

  • Watery consistency
  • Contains alcohol

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8. Skin Daily Vitamin B3 Niacinamide 5% Serum

Skin Daily Vitamin B3 Niacinamide 5% Serum boosts collagen to plump up mature skin. Hyaluronic acid restores and maintains the skin’s moisture barrier to prevent water loss. Niacinamide evens out the skin tone and tightens open pores. It effectively soothes acne, flare-ups, and the associated redness and scars. This serum works on the signs of aging – wrinkles, hyperpigmentation, and sun damage.

It deeply rejuvenates dull, dry, and crepey skin to give you a firmer, healthier, and youthful look. This niacinamide serum is vegan and cruelty-free. It is also free of parabens, phthalates, and synthetic preservatives. For best results, use this serum after cleansing and toning. Warm up a small pea-size amount of the serum by rubbing it between your hands and spread it evenly on the face and neck. Follow up the serum with a lotion or cream after 5 minutes.

Key Ingredients: Niacinamide and hyaluronic acid

Pros

  • Prevents moisture loss
  • Repairs sun damage
  • Tightens sagging skin
  • Vegan
  • Paraben-free
  • Cruelty-free
  • No preservatives
  • Phthalate-free
  • Non-greasy
  • Long-lasting
  • Spreads easily

Cons

  • May cause breakouts

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9. Bliss Glow & Hydrate Niacinamide + Hyaluronic Acid Day Serum

Bliss Glow & Hydrate Day Serum is formulated with special-grade antioxidant-rich niacinamide that leaves your skin glowing and fresh every day. It also contains hydrating elements like aloe leaf juice and hyaluronic acid that replenish the moisture and nutrients in dry and tired skin. Vitamin E provides superior antioxidant protection from environmental damage, aging, and inflammation. This serum reduces blemishes, dark spots, open pores, acne, and skin sensitivity. It smoothens the skin texture, brightens uneven skin tone, and lifts up your skin in the subtlest and most natural way. You can use it in your morning skin care routine before moisturizing. This formula does not weigh heavily on your skin or clog pores but leaves your skin with a faint honeysuckle fragrance.

Key Ingredients: Special-grade niacinamide, vitamin E, hyaluronic acid, aloe leaf juice

Pros

  • Minimizes open pores
  • Reduces blemishes and dark spots
  • Prevents skin damage
  • Improves skin texture
  • Evens out the skin tone
  • Soothes inflammation
  • Imparts a healthy glow
  • Vegan
  • Leaves no residue
  • Cruelty-free
  • Lightweight
  • Paraben-free
  • SLS-free
  • Pleasant fragrance
  • PETA-certified
  • Trendy packaging

Cons

  • Dries out the skin
  • May cause dry patches and flaking

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10. Best Serum For Mature Skin – QRxLabs Niacinamide + Retinol Serum

QRxLabs Niacinamide + Retinol Serum is a quick-absorbing, age-defying formula recognized by dermatologists. It deeply nourishes and hydrates the natural barrier of your skin. Its clinically-proven formula features moisturizing and anti-aging components like niacinamide, retinol, jojoba oil, vitamin E, retinol, propolis, and dandelion extracts. These ingredients work on softening fine lines, wrinkles, dark spots, and signs of photoaging. They boost collagen production to make your skin look firmer and brighter. Hydrating agents like aloe leaf juice, hyaluronic acid, geranium extract, and green tea extract restore the moisture and nutrient balance in dry and mature skin. Using this affordable serum regularly leaves your skin feeling radiant, youthful, and well-rested.

Key Ingredients: Niacinamide, retinol, aloe vera extract, vitamin E, jojoba oil, hyaluronic acid, geranium extract, propolis, and gotu kola extract

Pros

  • Hydrates the skin
  • Reduces acne scars and open pores
  • Improves skin elasticity
  • Reduces fine lines and wrinkles
  • Lightens dark spots
  • Offers deep hydration
  • Suitable for all skin types
  • Fast-acting formula
  • Cruelty-free
  • Dermatologist-recognized
  • Paraben-free
  • Silicone-free
  • Dermatologist-approved

Cons

  • Leaves a sticky residue
  • May cause skin discoloration

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11. Gia Naturals B3 Serum Niacinamide 5%

This vitamin B3 Serum by Gia Naturals uses the highest-quality niacinamide in a 5% concentration and is safe for all skin types. Its potent anti-inflammatory properties clear blemishes and uneven discoloration. Hyaluronic acid, aloe leaf juice, and other hydrating agents introduce moisture and nutrients in aging skin to reduce wrinkles, fine lines, open pores, and dullness. It makes your skin look plump and firm as it boosts collagen and fights free radical damage. This Gia Naturals serum is made only with pure, natural, and organic ingredients in a USFDA-registered facility to ensure safety and efficacy. It can be used on sensitive and irritated skin with minimum side effects.

Key Ingredients: Aloe leaf juice, niacinamide, glycerin, avocado oil, hyaluronic acid, vitamin-e, sunflower seed oil, neem seed oil, rosemary leaf extract, and sunflower seed oil

Pros

  • Reduces fine lines and wrinkles
  • Fights free radical damage
  • Boosts collagen production
  • Minimizes open pores
  • Makes the skin firm
  • Clears acne spots
  • Soothes inflamed skin
  • Cruelty-free
  • Reduces hyperpigmentation
  • Can be used on neck, hands, arms, legs
  • Suitable for skin types
  • Gets absorbed quickly
  • Vegan
  • Non-comedogenic
  • Offers smooth application

Cons

  • Feels sticky
  • May cause skin dullness

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12. Paula’s Choice BOOST 10% Niacinamide Booster

Paula’s Choice BOOST 10% Niacinamide Booster is a concentrated niacinamide serum that dramatically improves skin texture, tone, and elasticity. It softens the signs of aging and shrinks large, open pores. This booster also contains allantoin and licorice root extracts that soothe inflamed scars, acne, redness, and uneven skin tone. This hydrating serum rejuvenates the skin from within to make it look smooth, supple, and radiant. It is a lightweight, ultra-sheer formula that does not clog skin pores. The watery consistency ensures it spreads quickly and evenly and penetrates deep into the skin. You can use it alone or add it to your moisturizer or other treatments for great results.

Key Ingredients: Niacinamide, allantoin, punarnava extract, licorice extract, genistein, and sodium hyaluronate

Pros

  • Lightweight
  • Brightens the complexion
  • Shrinks open pores
  • Evens out the skin tone
  • Imparts a radiant glow
  • Soothes acne-prone skin
  • Non-greasy
  • Suitable for oily skin
  • Spreads easily
  • Mixes well with other products

Cons

  • Expensive
  • Too little quantity

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13. Best Vegan Serum – Genius Cure Niacinamide 12% Serum

Genius Cure Niacinamide 12% Serum is a vegan, high-performance formula that deeply nourishes and soothes sensitive and delicate skin. It offers a burst of hydration, improves the barrier function, and stimulates collagen production in mature skin. It shrinks open pores and prevents moisture loss that would otherwise cause dryness and dullness. Niacinamide and hyaluronic acid act together to make your skin look plump, soft, and well-hydrated.

Zinc PCA and citric acid fight the signs of sun damage, inflammation, hyperpigmentation, wrinkles, and fine lines. They tone down flare-ups and clear existing blemishes, scars, and dead tissue. When used regularly, the Genius Cure Niacinamide Serum makes your skin look and feel brighter, clearer, and firmer with comparatively fewer applications.

Key Ingredients: Niacinamide, Zinc PCA, sodium hyaluronate, and citric acid

Pros

  • Reduces hyperpigmentation
  • Tightens mature skin
  • Deeply nourishing formula
  • Offers gentle exfoliation
  • Shrinks large pores
  • Restores the moisture barrier
  • Reduces acne scars and blemishes
  • Reduce acne flare-ups
  • Non-toxic
  • Vegan
  • Suitable for sensitive skin
  • Affordable
  • Can be worn under makeup
  • Easy to use

Cons

  • Unpleasant fragrance
  • May cause breakouts

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These niacinamide serums are highly effective, versatile, and deliver long-term results. Wondering how they work on your skin? Find out more in the following section.

What Are The Benefits Of Using Niacinamide On Skin?

Niacinamide has potent anti-inflammatory and antioxidant effects on all skin types. It helps to:

  • Improve skin texture and elasticity
  • Strengthen the skin’s protective barrier
  • Reduce irritated or flaky skin caused by inflammation
  • Replenish natural lipids in the skin surface
  • Mitigate moisture loss
  • Maintain pore size in all skin types
  • Diminish under-eye concerns
  • Protect skin from sun damage
  • Soothe sensitivity and skin irritation

Niacinamide is essential for your skin. This versatile vitamin solves nearly all of the nagging skin concerns you have had at some point in time. And, the listed benefits apply to all skin types. But, how to pick the right serum for your skin? Read on to know more.

How To Pick The Right Niacinamide Serum For Your Skin

  • Niacinamide Concentration

5% niacinamide is the recommended dose that is safe and shows maximum efficacy. Opt for serums that have nearly 5% niacinamide. They take longer to show expected results but are, nevertheless, safer than 10 or 12% ones. Higher concentrations may cause niacinamide overload with moderate to severe side effects.

  • Active Ingredients

Choose serums with hydrating or moisturizing ingredients like hyaluronic acid, aloe leaf juice, zinc compounds, glycerin, allantoin, essential oils, nut butter, fatty alcohols, propolis/honey, and sunflower seed extract. Also, look for antioxidants like vitamins E, A, and C and extracts of green tea leaves, chamomile, licorice root, hibiscus flowers, and neem seeds. These active ingredients supplement niacinamide in delivering anti-inflammatory, anti-aging, and skin-renewal effects.

  • Skin Type

This is one of the most critical criteria in choosing the best serum. Most niacinamide serums are made for all skin types. Since they offer anti-inflammatory effects, they can be used on sensitive, delicate, and mature skin too. However, look out for individual ingredients that irritate your skin type particularly. It could be some essential oils, fragrances, nut derivatives, or flower extracts. As a measure of caution, read the serum contents from start to finish every time you make a purchase.

Keeping these points in mind, buy a niacinamide serum that fits your budget from the options listed above. Each product comes with a unique blend of active ingredients. Some of them are vegan, paraben-free, and cruelty-free as well. Use the buying guide to narrow down the most suitable match for your skin type. Use the niacinamide serum consistently before expecting any improvements because all good things take time! Grab a serum from the ones listed above to transform your skin from within.

Expert’s Answers For Readers’ Questions

What can you not mix with niacinamide?

You should not mix any acidic skin care ingredient with niacinamide. These include AHAs, BHAs, retinoic acid, and vitamin C. Exfoliants like salicylic acid, glycolic acid, etc., also don’t go well with it. They nullify the soothing effects of niacinamide.

When and how often should niacinamide be applied?

If tolerated well, you can use niacinamide twice a day. But, make sure you avoid using it with acidic components. You can apply niacinamide in the day and other acidic skin care products at night. Since it is non-acidic, niacinamide products blend safely with moisturizers, sunblock, and face makeup.

How long does niacinamide take to work?

If using you are using a 5% niacinamide product, it takes about 8-12 weeks to show visible results. This concentration is the safest to work with and causes no skin irritation. It is recommended to avoid using higher doses of niacinamide for quick results.

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Swathi Handoo

Swathi holds a Master’s degree in Biotechnology and has worked in places where actual science and research happen. Blending her love for writing with science, Swathi writes for Health and Wellness and simplifies complex topics for readers from all walks of life.And on the days she doesn’t write, she learns and performs Kathak, sings Carnatic music compositions, makes plans to travel, and obsesses over cleanliness.
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