Can You Use Hyaluronic Acid And Vitamin C Serum Together?

Written by Annie Jangam
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Vitamin C and hyaluronic acid (HA) will ring a bell if you have been reading the ingredient labels on your beauty products. They are known for their anti-aging properties, and are more often paired together. With the beauty market flooding with active and concentrated ingredients, there are good chances you will find these two on the shelves of your favorite store. But what is the big deal about them? How are vitamin C and hyaluronic acid beneficial for your skin?

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How Are Vitamin C And Hyaluronic Acid Good For Your Skin?

You have been taught the importance of vitamin C in a wholesome diet. You probably know how vital it is to keep your body’s natural defenses strong. However, did you know that it can also do wonders to your skin?

Vitamin C enhances the quality of your skin in two ways. Firstly, it stimulates the production of collagen. Secondly, it protects the skin from sun damage (1). Moreover, vitamin C also has the best antioxidant properties. It can neutralize the oxidants found in pollutants and protect your skin from free radical damage (1).

Vitamin C also helps reduce the premature signs of skin aging. It protects your skin from harmful UV rays (2). It also exfoliates your skin and eases any inflammation caused by acne.

Hyaluronic acid is a sugar your body produces naturally. It is found in the skin, eyes, and connective tissues. It is a humectant (aids hydration) (3). Hyaluronic acid creates a barrier by sealing the moisture inside your skin and improves your overall skin texture.

Your skin loses moisture as it ages. Hyaluronic helps maintain the water balance and makes your skin soft and plump. Moreover, it also may help reduce fine lines and wrinkles (3).

Now that you know what vitamin C and hyaluronic acid can do to your skin, let us understand if you can use them together.

Can You Use Hyaluronic Acid And Vitamin C Together?

Yes, you can use the two ingredients together and enjoy the unique benefits they bring to your skin. Generally, two counter-active chemicals can cause skin reactions. But you can rest assured with vitamin C and hyaluronic acid. They are effective together and are often used in several beauty products.

While Vitamin C will protect your face from damage and rejuvenate it by stimulating collagen production, hyaluronic acid will make it plump and soft. When you follow any beauty regime, the sequence of the products used is crucial to reap the maximum benefits. You may also use vitamin C and hyaluronic acid separately. If that is the case, which product should be used first?

What Should You Apply First: Hyaluronic Acid Or Vitamin C?

HA starts disintegrating in mixtures that have a pH level of less than 4 and more than 11 (4). On the other hand, the pH level of vitamin C should be less than 3.5 for getting absorbed into the skin properly (5).

Both these ingredients/products must be used after the toner. The golden rule is to use the thinnest product first and the thickest one last. Hence, you will have to apply vitamin C first and then move on to hyaluronic acid. However, leave a gap of a few minutes to allow vitamin C to penetrate your skin.

Since vitamin C is lighter and has a lower pH, it will quickly get absorbed into your skin (5). Applying hyaluronic acid afterward vitamin C will create a barrier (6). Moreover, vitamin C may dry your skin. Applying HA afterward will help restore skin moisture.

HA is available in a variety of products on the market. A cream-based formula will work wonderfully for dry and normal skin types, while a water-based product will deliver better results for combination or oily skin types.

While these ingredients can boost your skin health, using them right can multiply the benefits.

How Often Should You Use Hyaluronic Acid With Vitamin C To Improve Your Skin?

It is advisable to go slow while trying a new product on your face. Your skin could be sensitive to active ingredients like vitamin C and hyaluronic acid. In the beginning, use these serums on two different days a week and buffer them between your toner and moisturizer. You can preferably follow this regimen before bedtime (to better understand if your skin is sensitive to any of these products).

If everything goes well, you can start layering them together. The trick is to build these products into your skincare regime gradually before you start using them consistently in the mornings and nights.

As for the dosage, less is always more with such active ingredients. A pea-sized amount should ideally be enough for your face. Using more will not give you any better results. Take the product on your fingers and apply it evenly to your face.

Let us now check a quick DIY vitamin C serum with a hyaluronic acid recipe.

DIY Hyaluronic Acid And Vitamin C Recipe

If you want to use a single product containing these two potent ingredients sans other irritants, this quick DIY vitamin C serum with hyaluronic acid recipe can help. This recipe is a lot more cost-effective than one available on the market.

This recipe works because water has a pH of 7, and it will keep the HA stable. You need not worry if hyaluronic acid would lose its potency after a while. Also, while making your own serum, it is advisable to stick to a vitamin C concentration of 10 to 20% – as anything more can be too harsh on your skin. The MAP powder (the vitamin C) used in this recipe is stable and gets easily absorbed into the skin (7).


  • 2 teaspoons of hyaluronic acid serum
  • 3/4 teaspoon of magnesium ascorbyl phosphate (MAP) powder
  • 1 tablespoon of aloe extract
  • 2 tablespoons of distilled water

How To Make The Serum

  • Take a dark-tinted bottle.
  • Add all the ingredients into the bottle and shake it vigorously.
  • Your serum is ready once the MAP powder has completely dissolved.

Although you can use vitamin C and HA in combination, you need to be cautious while combining two active ingredients. Let us see a few general rules you are recommended to follow.

What Are The Rules For Combining Skin Care Products?

If you are concerned about using different products together, here are a few rules you can follow.

1. Understand The pH Balance

With an understanding of the pH balance of your skin and the active ingredients, you can avoid committing any cardinal mistakes while combining two potent compounds. The natural pH balance of your skin is around 4.7 and 5.7, making it slightly acidic.

Using pH-balanced products will help maintain the pH level of your skin. In other words, any product that has a pH between 4 and 7 should be good for your skin. Also, it is recommended to use products at a similar pH level.

For instance, retinol or vitamin A derivatives have a pH over 5, while vitamin C is more acidic at 3.5. Hence, these two should not be used together.

2. Water And Oil: Decide Which One Goes First

What happens when you mix oil and water? Oil floats on water and creates a barrier. Similarly, an oil-based product will block the penetration of a water-based gel or lotion. Thus, always use the latter first and move on to oil-based products.

3. Allow Each Product To Absorb

When using vitamin C and hyaluronic acid, ensure you have a few minutes for your skincare regime. Let each of your products sit for at least 30 seconds before applying the next. This method will ensure better absorption.

4. Find What Works For you

Your skin is unique, and what works for your friend may not work for you. It is all about finding what gives you better results. You can consult a dermatologist and see what would work best for you.

If you are looking for products containing vitamin C and HA, below are our recommendations.

Skin Care Products With Vitamin C And Hyaluronic Acid

1. Glo Skin Beauty Solar Shade SPF 50 – Gentle Suncare, for Sensitive Skin – Natural Mineral Face Sunscreen

Glo Skin Beauty Solar Shade SPF 50

This natural blend of active ingredients includes vitamin C and hyaluronic acid and is an elixir for sensitive skin. It has a lightweight formula and is free of artificial fragrances and colors. This all-in-one product will fortify your skin and protect it from harmful UV radiation.

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2. Vitamin C and Hyaluronic Acid Serum ampoule, Flavo-C Ultraglican by ISDIN

Vitamin C and Hyaluronic Acid Serum

Here is an anti-aging serum that will protect your skin from oxidative stress and reduce fine lines and wrinkles. The antioxidants in this formula will protect your skin from free radicals and also boost skin hydration.

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To Conclude

Adding vitamin C and hyaluronic acid to your skincare routine can do wonders for your skin. Apart from reducing fine lines and wrinkles, this powerful combination can rehydrate your skin and enhance its natural glow. The combination also protects your skin from harmful UV radiation. Start including products containing these ingredients into your skincare routine today. Use them regularly and see the results for yourself!

Frequently Asked Questions

What other product can you mix with hyaluronic acid?

HA is a good hydrating agent for any of your beauty products that may dehydrate your skin. For instance, retinol is known for its skin-renewing properties ( 8). But it also may cause your skin to become dry. HA can balance this out and boost the moisture levels in your skin.

What should you not mix with vitamin C?

Alpha hydroxy acids offer antioxidant benefits to the skin ( 9). However, a combination of AHAs with vitamin C can be highly acidic and cause skin issues.

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Annie Jangam is a Molecular Biologist with 7 years of research experience in Rice Functional Genomics and Nutrient Signalling with International Publications in Abiotic stress, Nitrogen, and G-protein signaling. She specializes in writing on Health and Wellness. She has been an avid reader since childhood and is passionate about stories that help decipher life and its meaning. She believes in Human Rights for all and that one should "love others like we love ourselves."