Mesotherapy For Hair – Procedure, Results, Side Effects, And More

Written by Arshiya Syeda

Hair loss is one of the most common problems today. Though losing 25 to 50 hair strands in a day is normal, sometimes, the hair loss can be a lot more and rapid, causing worry and concern. Mesotherapy may help prevent hair loss, improve hair quality, and stimulate hair growth. Scroll down to know about the process, cost, side effects, and more.

What Is Mesotherapy For Hair?

Hair mesotherapy is also known as mesoplasty or mesohair. It involves injecting medications directly into the scalp. This technique acts on the epidermis, dermal connective tissue, circulation, and the immune and neurosensory systems.

It can help in improving certain forms of alopecia like telogen effluvium, androgenetic alopecia, alopecia areata, and stress alopecia. However, there is very little scientific evidence to show that this technique can eliminate hair loss.

The objective of this treatment is to restore and increase microcirculation in the scalp, provide nutrients, slow down the shrinking of follicles, and stimulate hair growth. It claims that the following chemicals and ingredients can stimulate hair growth and encourage new hair production (1), (2), (3):

  • Biotin
  • Buflomedil
  • Dexenol
  • Dutasteride
  • Finasteride
  • Minoxidil
  • Organic silicium
  • Vitamins
  • Acetyl tetrapetide-3
  • Biochanin-A
  • PRP
  • Nano peptides
  • Cocktails

The materials used for mesotherapy can be classified as – principal/major ingredients (that are backed by scientific evidence and approved by the FDA) and complementary/minor ingredients (that claim to improve the existing condition). An effective cocktail contains at least two to three principal agents.

There is a lack of scientific research to establish which cocktail and application scheme are the most effective in hair mesotherapy to aid hair growth. The amounts of vitamins, enzymes, hormones, pharmaceuticals, homeopathic agents, natural plant extracts, and bioactive substances used in these injections depend on the doctor’s practice and experience.

History Of Mesotherapy

The term ‘mesotherapy’ was first coined by Dr. Michel Pistor in 1958. He used this as a pain-relieving technique to treat conditions in rheumatology, sports, traumatology, infectious diseases, and vascular diseases. Dr. Lionel Bissoon learned the technique in France and later popularized it in the US. Its cosmetic applications, particularly for the removal of fat and cellulite and treating hair loss, have recently received worldwide attention.

How Does Mesotherapy For Hair Loss Work?

Mesotherapy is a non-invasive and non-surgical cosmetic medicine treatment used to restore volume and luster to thinning hair. It involves inserting micro-injections of pharmaceutical agents, amino acids, vitamins, and others into the epidermal layer of the skin. This stimulates the mesoderm layer and encourages hair growth and promotes new hair production.

The technique is based on the fact that most hair loss problems occur due to hormone imbalances around the hair follicles (like DHT), lack of proper nutrients that aid hair health, and reduced blood circulation to the scalp.

The mesotherapy solution that is injected into the scalp contains a combination of specific chemicals, vitamins, co-enzymes, and amino acids that are tailored based on the patient’s requirements. Mesotherapy helps in restoring hormone balance gradually, which encourages the growth of new and healthy hair strands. Both men and women can benefit from this technique.

What Is The Process Of Mesotherapy For Hair?

Mesotherapy for hair is performed in two ways:

1. Chemical Mesotherapy

Ingredients like buflomedil, minoxidil, finasteride, dutasteride, biotin, vitamins, and organic silicium are injected into the skin’s mesoderm layer. These ingredients work together to stimulate natural hair growth by improving blood circulation, neutralizing excess DHT, reducing inflammation, and stimulating collagen production to stop hair loss.

2. Mechanical Mesotherapy

The doctor creates micro-perforations in the affected area, which induces hair growth. This motion triggers collagen and elastin production. These help in the formation of new tissues in your hair. During this process, there is no damage to the existing collagen.

How Long Does The Treatment Last?

The duration of the treatment depends on the individual, but on average, you will need the therapy for about four months, once a week.

The treatment usually spans eight sessions, one every week, for half an hour each. One must be patient and composed while taking this treatment as visible results are only observed after the fifth session.

Of course, once your body starts responding to the treatment, the duration and frequency of the treatment will be reduced.

What Are The Side Effects Of Mesotherapy?

A study was done to demonstrate the late-onset effects of mesotherapy for alopecia. Three patients with androgenetic alopecia experienced hair loss after previously uneventful mesotherapy sessions for a year (4). The study concludes that mesotherapy for androgenetic alopecia may induce hair loss and scarring.

In another study, two patients developed patchy alopecia after undergoing mesotherapy for the treatment of androgenetic alopecia (5).

It may also cause acute complications like scalp abscesses (6). Some people may also experience bruising, edema, headache, itching, and pain (7).

Who Should Not Go For Mesotherapy For Hair Loss?

Do not opt for mesotherapy if you (7):

  • are allergic to any of the substances used in mesotherapy
  • have diabetes, liver, kidney, or cardiac issues
  • are pregnant or lactating
  • are on anticoagulants
  • have an infection or lesion in the affected area.

How Much Does Mesotherapy Cost?

The cost of mesotherapy depends on the type of treatment and the number of sessions. A single session costs anywhere between $250 and $600. As mesotherapy is a non-invasive cosmetic technique and does not involve surgery, insurance companies usually don’t cover the cost.

Care And Maintenance

This treatment may prevent the need for hair transplant surgeries and other expensive and painful alternatives. However, for best and speedy results, the patient should maintain a healthy diet, eliminate the intake of junk food and toxins, and follow a regular fitness regimen.


Hair mesotherapy is a non-surgical and relatively painless injection technique. Despite little research on its use and effectiveness, hair mesotherapy has become extremely popular in the last few years. It is critical to use the correct cocktail and injection technique to achieve the right results. However, be wary of the contraindications and side effects.

Frequently Asked Questions

Is mesotherapy for hair painful?

No, if done properly, it is one of the least painful hair regenerative methods out there.

How soon can I expect to see results after the first treatment?

The results of any hair restoration treatment always vary between individuals, but in most cases, it will take 2–3 months before results are noticeable.

Is mesotherapy for hair permanent?

Unfortunately, the results do not last long in mesotherapy for hair.

How is PRP different from mesotherapy?

PRP is a more complex procedure than mesotherapy. In PRP, blood is withdrawn from the patient and checked for analysis. After a complicated series of processes, clear blood plasma and concentrated rich plasma are injected into the person’s scalp to stimulate hair growth.


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Arshiya Syeda is an editor and certified counselor. Ever the lover of the written word, she served on the editorial boards of her school and college newsletters. Writing articles on hairstyles, hair care, and nutrition helped her combine her love for reading, writing, and research. As an editor, she helps her team members deliver polished and meticulously researched content. Arshiya is fluent in English, Urdu, and Hindi and aims to become a multilinguist by learning German and teaching herself American Sign Language (ASL).