4 Side Effects Of Mulberry You Should Know

Here we go 'round the mulberry bush, the mulberry bush—with a dose of warnings!

By Tanya Choudhary

Mulberry is known for its antioxidant properties and many health benefits. However, you must be aware of the potential side effects of mulberry as well. Commonly consumed freshly picked, or preserved and made into juices, jams, and jellies, mulberries enrich you with many vital vitamins and minerals. Additionally, the mulberry leaf extract is also used in many traditional medicines and treatments. However, there are certain things you need to keep in mind if you like taking mulberry too often! To help you know more, we have listed down the possible risks and side effects of mulberry for you.

4 Side Effects Of Mulberry You Should Know

1. May Lead To Hypoglycemia

Mulberries are known to lower blood sugar. In studies, mulberry extracts could lower blood sugar levels in normal and diabetic mice (1), (2), (3). In humans, mulberry tea suppresses the postprandial rise of blood glucose levels after 90 minutes since its consumption (4). Mulberry leaf extracts, like α-glucosidase, may help delay carbohydrate digestion (4), (5). This can lead to a sudden drop in blood glucose levels, especially in those already on diabetic medication. As per anecdotal evidence, the symptoms may include hunger, headache, blurred vision, excessive sweating, dizziness, confusion, and tremors. Mulberries, hence, must be eaten with caution. It is important to consult a licensed medical professional if you are planning on taking mulberry extract supplements to treat diabetes or obesity.

2. May Cause Gastrointestinal Discomfort

Mulberries and their derivatives may cause indigestion, nausea, diarrhea, and bloating. In a study, patients who took a mulberry leaf tablet dyslipidemia treatment experienced mild diarrhea (26%), dizziness (8.7%), or constipation and bloating (4.3%) (6). Moreover, the latex (milky white sap) from mulberries is toxic, especially to insects and caterpillars (7). This latex can cause mild skin irritation in humans. It is not advisable to ingest it as it may cause stomach upset, bloating, and diarrhea.

3. May Hinder Carbohydrate Absorption

Mulberries are known to hinder carbohydrate absorption (8). Research shows that inhibition of carbohydrate absorption may help in weight control and diabetes treatment.  A study published in The American Journal of Clinical Nutrition reports that tea extracts (including mulberry) resulted in carbohydrate malabsorption (8). This property of mulberry can interfere with the optimal absorption of nutrients and lead to detrimental effects in the body.

4. May Have A Detrimental Effect On Kidneys

Mulberry leaves may help relieve the symptoms of gout by lowering uric acid levels (9). Hence, avoid taking mulberry leaves if you are already on medication to lower uric acid levels. Mulberries are also high in potassium, which is integral for the proper functioning of the body (10). Anecdotal evidence suggests that high levels of potassium may result in dehydration and internal bleeding. High potassium levels may also cause fatigue, numbness, nausea, chest pain, irregular heartbeats, and palpitations. Hence, people with chronic kidney disease must limit or even avoid mulberry intake.

The side effects of mulberries are generally associated with their overconsumption. If taken in excess, mulberries may trigger hypoglycemia. They also cause gastrointestinal discomfort and trigger nausea, bloating, and diarrhea. These berries may also interfere with carbohydrate malabsorption. Individuals with chronic kidney disease must be wary of mulberries. However, those with no health complications can stick to a moderate intake of mulberries.

Frequently Asked Questions

Can you be allergic to mulberries?

Yes. Although rare, people can be allergic to mulberries. They can cause sneezing, runny nose, and watery eyes. Consult a licensed professional if these symptoms persist.

Can mulberries get you high?

Unripe mulberries can cause mild hallucinations and affect the central nervous system. However, further studies are needed to understand the exact cause, dose, and mechanism.

How do you eat mulberries?

You can eat them fresh. Make sure you wash them thoroughly before you consume them. Mulberries, fresh or frozen, go well with porridge, smoothies, and salads. You can also have mulberry-based desserts and cakes.

Can mulberries increase skin cancer risk?

There is no scientific evidence to support this claim. However, artificially lightening your skin may increase the risk of skin cancer.

Do mulberries interfere with chemotherapy?

It is better to avoid mulberries if you are undergoing chemotherapy unless the doctor specifically permits their use. It is believed that the anti-cancer properties of mulberry extracts may interfere with the chemotherapy protocol. However, more research is warranted in this regard.


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  1. Induction of Biologically Active Flavonoids in Cell Cultures of Morus nigra and Testing their Hypoglycemic Efficacy
  2. Antihyperglycemic effect of crude extracts of some Egyptian plants and algae
  3. Morus nigra leaf extract improves glycemic response and redox profile in the liver of diabetic rats
  4. Reduction of postprandial hyperglycemia by mulberry tea in type-2 diabetes patients
  5. Phenolic compounds isolated from Morus nigra and their α-glucosidase inhibitory activities
  6. Efficacy of mulberry leaf tablets in patients with mild dyslipidemia
  7. Mulberry latex rich in antidiabetic sugar-mimic alkaloids forces dieting on caterpillars
  8. An extract of black, green, and mulberry teas causes malabsorption of carbohydrate but not of triacylglycerol in healthy volunteers
  9. Metabolic Effects of Mulberry Leaves: Exploring Potential Benefits in Type 2 Diabetes and Hyperuricemia
  10. Potassium and health
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Tanya is an ISSA certified Specialist in Fitness & Nutrition. She specializes in writing articles on ingredients that benefit skin,... more