13 Best Drugstore Vitamin C Serums, As Per An Expert – 2025
Preserve your youthful glow for the longest time with these affordable vitamin C serums.
Diane Howard, RN, is a certified cosmetic nurse and the founder of Esthetic Finesse. She has received extensive training under esteemed physicians and nurses in the valley. After recognizing that esthetic medicine demands a creative mastery akin to that found in other art forms, Diane established Esthetic Finesse to showcase her exclusive brand of beauty services.
Read full bio of Diane Howard
Experience: 3 yearsKrati is an associate commerce editor, a certified skin care coach, and a beauty enthusiast. She has a master’s degree in advertising and publishing relations from DAVV University and three years of experience in writing and editing for different niches.
Read full bio of Krati Darak
Experience: 5 yearsMedha Deb is a commerce editor with a master's degree in applied linguistics from the University of Hyderabad, which has allowed her to develop a deep understanding of language and its application in various contexts. She specializes in the areas of beauty, health, and wellness and is committed to ensuring that the content on the website is of the highest quality.
Read full bio of Medha Deb
Experience: 4 yearsShiboli has a master’s degree in English literature from The English and Foreign Languages University, Hyderabad, and is a certified skincare coach with four years of experience. As a commerce editor, she guides her team members on the best practices to create crisp and authentic content.
Read full bio of Shiboli Chakraborti
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Vitamin C, also known as ascorbic acid, is an antioxidant and a popular ingredient in many rejuvenating skin care products. Diane Howard, certified cosmetic nurse and the founder of Esthetic Finesse, says, “Vitamin C is a secret ingredient when it comes to achieving healthy and radiant skin. This potent antioxidant not only helps protect the skin from environmental damage but also promotes collagen production, resulting in firmer and more youthful-looking skin. Vitamin C also brightens the skin tone, fades dark spots, and reduces the appearance of fine lines and wrinkles.” The good news is that you can get this powerful element in the form of the best drugstore vitamin C serum. Here is why you should be just as ecstatic as we are – vitamin C aids in the neutralization of free radicals and the formation of collagen. For you, this means two things – it can reduce age-related skin defects such as wrinkles, fine lines, and sagging skin, and by increasing collagen levels, new cells can grow more quickly, resulting in brighter, glowing, and youthful skin.
So, without any further ado, take a look at the top13 best drugstore vitamin C serums for glowing skin. Scroll down.
In This Article
The 13 Best Drugstore Vitamin C Serums For Glowing Skin – 2025
1. Best Overall: TruSkin Naturals Vitamin C Professional Facial Serum
TruSkin Naturals Vitamin C Professional Facial Serum is an antioxidant-rich formulation that helps to revitalize the skin and make it look youthful, brighter, and radiant. This drugstore antioxidant serum is enriched with aloe vera, hyaluronic acid, vitamin E, witch hazel, and jojoba oil among other skin-friendly organic ingredients. The formulation of this plant-based, natural vitamin C serum for face helps to increase the production of new cells by boosting the collagen. It helps neutralize free radicals and even out the skin tone at the same time providing protection against harmful UV rays.
Pros
- Offers sun protection
- Radiance-boosting
- Paraben-free
- Sulfate-free
- Phthalate-free
- Fragrance-free
- Cruelty-free
- Vegan
- Clinically-tested
- Dermatologist-tested
Cons
- Might cause allergic reactions for users with sensitive skin
Pro Tip
Why We Think It's Worth Buying
This product is so liked by shoppers that it has gained over 23,589 great reviews on Amazon.
2. Best Anti-Aging: InstaNatural Vitamin C Serum
Reduce the visible signs of aging with the regular use of InstaNaturals Vitamin C Serum. The formulation of this budget-friendly vitamin C serum includes ingredients like hyaluronic acid, witch hazel, sea buckthorn oil, plant stem cells, algae extract, licorice, green tea, pomegranate, argan, grapefruit, carrot, camellia, etc among others. This drugstore vitamin C serum with ferulic acid helps in minimizing the appearance of signs of aging and skin imperfections, boosting collagen to make the skin look firm, and helping one to maintain the natural glow and youthfulness of the skin intact. If you want to find out more about this skin care product and its usage through a tester’s experience, make sure to check out this review on YouTube.
Pros
- Collagen-boosting
- Cruelty-free
- Paraben-free
- Mineral oil-free
- Natural ingredients
Cons
- Users with sensitive skin might develop allergic reactions
Why We Think It's Worth Buying
With over 7,297 reviews, this product has become a fan favorite among users.
3. Best Collagen Boost: Sérumtologié C Serum- 22
Mature skin is more likely to be prone to dryness and other skin-related issues. But combating them becomes easier with the use of C Serum- 22 by Serumtologie. This is one of the highest quality vitamin C serums and is comprised of the extracts from a host of potent ingredients like gotu kola, wild dandelion, wild geranium, aloe vera, witch hazel, hyaluronic acid, jojoba oil, vitamin E and ferulic acid among others. This drugstore vitamin C serum for acne prone skin helps to reduce the visible signs of aging, boosts collagen in the skin, neutralizes free radicals, and minimizes the imperfections of the skin, leaving the user with naturally youthful and brighter-looking skin.
Pros
- Vegan
- Cruelty-free
- Paraben-free
- Phthalate-free
- Sulfate-free
- Aroma-free
- Propylene-free
- Glycol-free
Cons
- Some users might find the skin becoming too dry and tight after using the product
Why We Think It's Worth Buying
It has gained over 4,268 positive reviews on Amazon, making it an all-time best-seller.
| TruSkin Naturals Vitamin C Professional Facial Serum Best Overall | InstaNatural Vitamin C Serum Best Anti-Aging | Sérumtologié C Serum- 22 Best Collagen Boost | |
|---|---|---|---|
| Skin Type | Oily, Combination, Sensitive, Dry, Normal | All | combination, oily, dry |
| Dimensions | 1.5 x 1.5 x 4 inches | 3.5 x 2 x 2 inches | 1 x 1 x 3.5 inches |
| Weight | 1 Ounces | 2.24 Ounces | 1.15 Ounces |
| Rating | |||
| Reviews | 23,589 | 7,297 | 4,268 |
| Price | $21.97 | $21.95 | $35.0 |
4. Best Dermatologist-Tested: L’Oreal Paris Skincare Revitalift Derm Intensives Vitamin C Serum
L’Oreal Paris Skincare Revitalift Derm Intensives Vitamin C Serum is formulated with 10% pure vitamin C. This affordable vitamin C serum helps even out the skin tone and diminishes the appearance of dark spots, wrinkles, pores, and other skin imperfections upon regular usage. Free from harsh chemicals and dyes, this is one of the best over the counter vitamin C serums. It comes in an airtight metal tube so that the efficacy and stability of the product increases. This good drugstore serum leaves the user with a brighter skin and helps the skin heal from imperfections with time. If you need further convincing, check out the reviewer’s experience with the vitamin C product in this YouTuber’s review out.
Pros
- Tightens pores
- Paraben-free
- Fragrance-free
- Mineral oil-free
- Dermatologically tested
- No synthetic dyes
- Non-comedogenic
Cons
- Some users might develop allergic reactions
- Might leave the skin greasy or sticky
Why We Think It's Worth Buying
A whopping 4,331 reviews on Amazon make it obvious that users genuinely love this product.
5. Best For Glowing Skin: La Roche-Posay Pure Vitamin C Face Serum
Everyone wishes to have radiant skin irrespective of their age. Keeping the glow of the skin intact is now easier with the usage of La Roche-Posay Pure Vitamin C Face Serum. This drugstore sensitive skin-friendly vitamin C serum is formulated with 10% pure vitamin C, salicylic acid, hyaluronic acid, neuro sensine and other enriching ingredients. Lauded as one of the best OTC vitamin C serums, this dermatologically-tested budget vitamin c serum helps reduce the appearance of hyperpigmentation, visible signs of premature aging and skin imperfections at the same time neutralizing the free radicals and leaving the user with a brighter, youthful skin.
Pros
- Dermatologist tested
- Ophthalmologist-tested
- Oil-free
- Non-comedogenic
- Allergy tested
- Paraben-free
Cons
- Might cause allergic reactions for users with sensitive skin
6. Best For Dry Skin: DERMA E Vitamin C Concentrated Serum
The Derma E Vitamin C Concentrated Serum contains hyaluronic acid, making it ideal for dry skin. It also contains aloe vera leaf juice and glycerin, which act as humectants and soothe the skin. The green tea leaf extract reduces inflammation. Capric Triglyceride, when combined with Vitamin C, works wonders as an antioxidant and helps reduce skin dryness and lock in moisture. The moisturizing serum makes skin supple, reduces dark spots, reduces the signs of aging, and evens out the skin tone.
Pros
- Dermatologist-recommended
- Eco-ethical
- Cruelty-free
- 100% vegan
- Paraben-free
- Sulfate-free
- Mineral oil-free
- Petrolatum-free
- Lanolin-free
- Gluten-free
- Soy-free
- No GMOs
Cons
- Might cause purging for some
Pro TipWhy We Think It's Worth Buying
This product has received 4,025 reviews from customers on Amazon, indicating its popularity and reliability.
7. Best For All-Skin Types: Mario Badescu Vitamin C Serum
The Mario Badescu Vitamin C Serum is an antioxidant-enriched formula that makes your skin radiant and glowing. This lightweight serum delivers a youthful-looking complexion. The vitamin C in the formula is an antioxidant that protects your skin against free radical and sun damage. It brightens dull skin, helps eliminate dark spots, and fights signs of aging while evening out skin tone. The formula is also infused with a topical form of collagen, which keeps your skin firm, hydrated, and conditioned. The sodium hyaluronate, which is a derivative of hyaluronic acid, when combined with collagen, moisturizes and smoothens out your skin to deliver luminous and glowing skin. It also contains ever-so-soothing lavender oil, which has a calming effect on your skin.
Pros
- Promotes youthful complexion
- Lightweight
- Paraben-free
- Synthetic fragrance-free
- Cruelty-free
Cons
- Not suitable for acne-prone skin
8. Best Quick Results: Eclat Skincare 20% Vitamin C Facial Serum
The Eclat Skincare’s 20% Vitamin C Facial Serum provides the most potent formulation of sodium ascorbyl phosphate and hyaluronic acid. The scientifically formulated serum helps address hyperpigmentation quickly and keeps the skin hydrated and supple. This serum, prescribed and validated by leading dermatologists, contains additional collegial ingredients like retinol, jojoba oil, vitamin E, aloe vera, and MSM, which accelerate skin renewal and new cell turnover. The specific formulation fights free radicals, reduces wrinkles, and restores the youthful glow of your skin.
Pros
- Paraben-free
- Vegan
- Cruelty-free
- Silicone-free
- Quick results
Cons
- Might get oxidized if not stored properly
9. Best Natural Ingredients: Lezuna Premium Vitamin C Serum
Lezuna Premium Vitamin C Serum helps in the minimization of signs of aging by boosting collagen and aiding in production of new cells. A rich formulation of this budget-friendly vitamin C serum with other potent ingredients like hyaluronic acid, ferulic acid, vitamin E, aloe vera, jojoba oil, and many more ensures maximum benefits to the skin. This drugstore vitamin C serum with ferulic acid helps reduce the appearance of wrinkles, fine lines, dark spots, uneven skin tones, and other such skin imperfections and leaves the user with skin that emanates a soft and supple glow from within.
Pros
- Naturally derived ingredients
- Cruelty-free
- Paraben-free
- GMP certified
Cons
- Might leave a sticky feeling on the skin upon usage in some cases
10. Best Skin Protection: Cerave Skin Renewing Vitamin C Serum
Reduce visible signs of aging and give your skin a radiant makeover with the Cerave Skin Renewing Vitamin C Serum. This high-potency vitamin C serum is packed with potent antioxidant properties that help in defending your skin against free radicals. It tones the skin evenly, makes it plump, and reduces fine lines and wrinkles. The serum has 10% pure vitamin C which makes your skin radiant and healthy. The serum also contains hyaluronic acid to improve skin hydration, three essential ceramides to repair skin barrier, and vitamin B5 that restore your skin’s protective barrier. It comes in protective packaging to help prevent oxidation.
Pros
- 10% pure vitamin C
- Skin-smoothing and firming
- Allergy-tested
- Fragrance-free
- Paraben-free
- Non-comedogenic
- Dermatologically approved
- Suitable for all skin types
- Ideal for sensitive skin
- Easy to use
Cons
- Strong smell
Why We Think It's Worth Buying
The product has more than 2,109 reviews and is a top choice all around the world.
11. Best Organic: No B. S. Vitamin C+E Serum for Face
Say no to skin imperfections and signs of aging by using the Vitamin C+E Serum For Face by No B.S. This drugstore hyaluronic acid serum is formulated with organic ingredients like pomegranate, green tea, hyaluronic acid, gotu kola, vitamin E, and others. With the regular use of this drugstore vitamin c serum with ferulic acid, one can reap many skin benefits like boosting collagen to increase the cell production, neutralize free radicals, reduce signs of aging, and minimize the appearance of skin imperfections. Flaunt youthful skin that radiates and glows naturally with this amazing serum.
Pros
- Vegan
- Paraben-free
- Gluten-free
- Sulfate-free
- Cruelty-free
- Fragrance-free
- Phthalate-free
Cons
- Might cause allergic reactions in some cases
12. Best 86% Pure Vitamin C Formula: Minimalist 16% Vitamin C Serum
The Minimalist 16% Vitamin C Serum is highly popular for giving you glowing and radiating skin. This results-driven serum is powered by a stabilized Vitamin C derivative known as Ethyl Ascorbic Acid; it is 86% pure form of Vitamin C. Inclusion of vitamin E & ferulic acid together improves Vitamin C’s efficacy. The formula also has fullerenes (C60), a more potent, new-age antioxidant that works twice as much to boost the skin’s radiance and fights visible signs of aging. This serum reduces skin damage and redness and improves skin elasticity and texture.
Pros
- Skin-brightening and tightening
- Suitable for all skin types
- Improves rough skin texture
- Fragrance-free
- Essential oil-free
- Non-comedogenic
- Irritants-free
- Dermatologically tested
Cons
- Limited shelf life
- Not suitable for sensitive and acne-prone skin
13. Best pH-balancing: Naturium Vitamin C Complex Face Serum
The Naturium Vitamin C Complex Face Serum has a high concentration of pE, ascorbic acid, and a bioactive fruit blend. It helps to brighten the overall complexion and increases collagen production, protecting the skin from environmental stressors that can cause fine lines and discoloration. The key ingredients are vitamin C, hyaluronic acid, and vitamin E help to neutralize free radicals, fade dark spots, and restore the skin’s natural glow.
Pros
- Hydrating
- Skin-rejuvenating
- Cruelty-free
- Paraben-free
- Vegan
- Gluten-free
- Fragrance-free
Cons
- May not suit acne-prone skin
Buying Guide
How do you choose vitamin C serum?
Vitamin C is an important ingredient when it comes to skincare. Using a vitamin C serum on a daily basis can be very beneficial for the skin. On one hand there are ingredients that aid vitamin C in the maintenance of the skin, some ingredients can prove to be disastrous as well. As you set out to buy a vitamin C serum for yourself, let us shed some light on the points to remember before choosing the best one for yourself for visible results:
- Ingredients- The best drugstore vitamin C serum would have supporting ingredients like ferulic acid, vitamin E, and hyaluronic acid. But ingredients like retinol, niacinamide, benzoyl peroxide and AHAs/BHAs would not be recommended as they may cause side effects.
- Packaging- A vitamin C serum should be ideally packed in a glass bottle that is tinted in a shade of brown or any other dark color. It should have minimum contact with heat and air as they may degrade the quality of the content.
- Form- The best form of vitamin C available for use would be L-ascorbic acid. This is the most effective of all other vitamin C derivatives, hence widely used for skincare.
- Concentration- The ideal concentration of vitamin C in a serum would be 10-20%. A concentration of less than 10% wouldn’t be very effective, while a concentration of more than 20% might lead to skin irritation or other side effects.
The Bottom Line
If you want to keep your skin’s youthfulness intact, Vitamin C serums are the way to go! Vitamin C can help you restore the glow in your skin as it packs the goodness of antioxidants and eliminates premature signs of aging. It also keeps your acne, spots, and blemishes at bay. There are many Vitamin C serums that boost collagen and increase the production of new cells. Moreover, these serums are made with skin-friendly constituents that help in protecting your face from harmful UV rays and sun rays. The InstaNatural Vitamin C Serum is an affordable choice that is suitable for all skin types, while the La Roche-Posay Pure Vitamin C Face Serum helps exfoliate the skin to remove dead skin cells and works well on sensitive skin. The DERMA E Vitamin C Concentrated Serum quickly absorbs due to its non-greasy and lightweight texture and is suitable for all skin types. However, if you are someone with sensitive skin, it is always wise to check out the skin care ingredients thoroughly to effectively avoid skin damage or irritation. The serums that are free of paraben, phthalate, and sulfate are the best of the lot.
Frequently Asked Questions
What percent vitamin C serum is the most effective?
The best drugstore vitamin C serum should have a concentration between the range of 10-20 percent. Anything less than that wouldn’t be very effective and anything more than that might cause irritation on the skin.
Which one is better: hyaluronic acid or vitamin C?
Hyaluronic acid helps the skin retain its moisture and keeps it hydrated while vitamin C helps boost collagen and in turn cell production. Both provide the skin with important nutrients, hence it is advisable to use a serum that incorporates the benefits of both these skincare essentials.
Does vitamin C serum lighten skin?
Yes. Vitamin C inhibits the melanin production of the skin and helps minimize the appearance of dark spots and uneven skin tone, resulting in instant lightening of the skin.
Does vitamin C fade dark spots?
Yes. Vitamin C is known to reduce the appearance of dark spots and brighten the skin.
What can you not mix with vitamin C serum?
Benzoyl peroxide, retinol, niacinamide, and AHAs/BHAs are ingredients that should not be mixed with Vitamin C as they might prove to be disastrous for the skin.
Do I need a moisturizer after vitamin C serum?
Yes. Apply a moisturizer after using the vitamin C serum sinks in so that the active ingredients in the serum start working and then the goodness is locked in by your moisturizer.
Can you use vitamin C serum under the eyes?
Yes. Vitamin C serum is completely safe to be used under your eyes. It minimizes dark circles, reduces discoloration under the eyes, and hydrates the under-eye area.
Can a teenager use Vitamin C serum?
Yes. Teenagers can use Vitamin C serum. Just make sure to check the pH level of the product to choose the suitable serum for your skin type. Vitamin C serum is used for uneven pigmentation and dark spot. It protects you from harmful rays of the sun and environmental stresses. It helps to build collagen and has antioxidant properties which strengthen the SPF.
Why Trust StyleCraze?
Krati Darak is a skin care enthusiast who is fond of researching ingredients and reviewing products. She conducted an extensive research to understand the product specifications and analyzed the user reviews to compile this list for her readers. The recommended drugstore vitamin C serums add a healthy glow to your skin. They can also help you achieve bright, youthful skin.
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