The 13 Best Drugstore Wrinkle Creams Of 2022 That Actually Work

Bid adieu to dullness and age spots by applying these affordable skincare formulas.

By Vaishnavi Kothuri, Certified Skin Care Coach
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Your skin loses its elasticity with age and becomes saggy, dull, and lifeless. It also may develop wrinkles and fine lines. This is where the best drugstore wrinkle creams can help. They offer an affordable way to reduce the appearance of wrinkles and keep your skin youthful. In this article, we have listed the 13 best drugstore wrinkle creams for aging skin. Scroll down and check them out.

Our Top Picks
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Best Vegan:LilyAna Naturals Retinol Cream for Face
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Best For Aging Signs:Neutrogena Rapid Wrinkle Repair Moisturizer
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Best Dermatologically-Tested:RoC Retinol Correxion Deep Wrinkle Night Cream
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Best Fragrance-Free:Eucerin Q10 Anti-Wrinkle Face Cream
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Best For Skin Firmness:Young Secret Repair Firming Nourishing Cream
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Best For Blemishes:Body Merry Retinol Surge Moisturizer
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Best Non-Greasy:NatureWell Clinical Retinol Advanced Moisture Cream
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Best Dye-Free:InstaNatural Vitamin C Moisturizer
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Best Hypoallergenic:Pond’s Rejuveness Anti-Wrinkle Cream
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Best Fragrance-Free:CeraVe Skin Renewing Day Cream
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Top 13 Drugstore Wrinkle Creams To Use In 2022

1. Best Vegan:LilyAna Naturals Retinol Cream for Face

LilyAna Naturals Retinol Cream For Face is an advanced formula to slow down aging. It is a lightweight over the counter wrinkle cream that helps in lifting, brightening and rejuvenating the skin. Packed with natural skincare essentials like retinol, hyaluronic acid, aloe vera, green tea, shea butter, jojoba, vitamin A and vitamin E among others, this cheap anti-wrinkle cream does wonders to your face. It helps in the reduction of wrinkles, pigmentation, fine lines, crow’s feet, dark circles, blemishes and keeps the moisture of the skin intact to make it look bright and supple. Go through the video for a detailed review of the LilyAna Naturals Retinol Cream for Face.

Pros

  • Paraben-free
  • Phthalate-free
  • SLS-free
  • Cruelty-free
  • Vegan
  • Non-comedogenic

Cons

  • Users with sensitive skin might have allergic reactions

2. Best For Aging Signs:Neutrogena Rapid Wrinkle Repair Moisturizer

Keep the youthful glow of the skin intact with the usage of Neutrogena Rapid Wrinkle Repair Moisturizer. The presence of retinol, hyaluronic acid, and glucose complex in this drugstore anti-aging cream helps in warding off the signs of aging like wrinkles, crow’s feet, blemishes, fine lines, etc. It is one of the most effective drugstore wrinkle cream as it moisturizes dry skin and keeps it hydrated and strengthens the skin from within. A clinical trial done on a few subjects has shown visible results in just a week. What’s best is that you also get protection from UV rays of the sun as this potent wrinkle cream has a broad spectrum SPF 30 sunscreen. Check this video to understand the Neutrogena Rapid Wrinkle Repair Moisturizer better.

Pros

  • Paraben-free
  • Phthalate-free
  • Cruelty-free
  • Natural ingredients

Cons

  • Might cause allergic reactions for users with sensitive skin

3. Best Dermatologically-Tested:RoC Retinol Correxion Deep Wrinkle Night Cream

The Retinol Correxion Deep Wrinkle Night Cream from RoC helps you wake up with a rejuvenated skin that emanates a soft youthful glow. It is because of the common belief that the skin is most receptive during night time. The clinically proven formulation of this drugstore deep wrinkle cream includes collagen boosting retinol that helps in the production of new cells. This in turn, aids in the renewal of the skin. This drugstore anti-aging night cream minimizes the appearance of wrinkles, fine lines, crow’s feet and other age-related skin imperfections, leaving you with flawless-looking skin. If you want to better understand the RoC Retinol Correxion Deep Wrinkle Night Cream, check this video.

Pros

  • Paraben-free
  • Phthalate-free
  • Dermatologically tested
  • Non-comedogenic
  • Clinically proven

Cons

  • Some users might have allergic reactions to the product

4. Best Fragrance-Free:Eucerin Q10 Anti-Wrinkle Face Cream

Eucerin Q10 Anti-Wrinkle Face Cream is a skincare innovation which helps you in maintaining a bright and youthful appearance. This drugstore wrinkle product for mature skin is enriched with a potent formulation of coenzyme Q10, antioxidants, vitamin E, and beta-carotene among others. All these help in the reduction of the signs of aging, neutralizing free radicals, aiding cell production by boosting collagen and improves skin elasticity. Get rid of wrinkles, fine lines, crow’s feet, blemishes and other age-related skin issues and embrace the glow of younger-looking skin that is brighter and supple.

Pros

  • Fragrance-free
  • Alcohol-free
  • Non-comedogenic
  • Dermatologically recommended

Cons

  • Might not suit people with sensitive skin

5. Best For Skin Firmness:Young Secret Repair Firming Nourishing Cream

Reduce fine lines and wrinkles with the Young Secret Repair Firming Nourishing Cream. This cream replenishes lost moisture, deeply hydrates your skin, and firms the fine lines. It is infused with key ingredients to offer anti-aging effects. In addition, the potent blend of these ingredients provides youthful skin, makes it soft, and nourishes your skin.

Pros

  • Paraben-free
  • Phthalate-free
  • SLS-free
  • SLES-free
  • Suitable for all skin types
  • Skin-friendly

Cons

None

6. Best For Blemishes:Body Merry Retinol Surge Moisturizer

Keep the natural glow of your skin intact with the Body Merry Retinol Surge Moisturizer. It is made from a mix of potent ingredients like retinol, collagen, hyaluronic acid, aloe vera, sunflower, jojoba, dandelion, and green tea among others. This powerful formulation makes it one of the best drugstore anti-wrinkle creams that help fight the visible signs of aging. It also aids in keeping the skin plump, firm, tight, and helps restore the youthfulness of the skin.

Pros

  • Cruelty-free
  • Fragrance-free
  • Non-greasy
  • Lightweight
  • Nature-friendly ingredients

Cons

  • Might cause allergic reactions in some cases due to clogged pores

7. Best Non-Greasy:NatureWell Clinical Retinol Advanced Moisture Cream

Rejuvenate your skin with the Retinol Moisturizing Cream from NatureWell Clinical. It is formulated with micro-encapsulated retinol that promotes elasticity and firmness of the skin, leaving it even-toned and smooth. It thoroughly moisturizes the skin, gets quickly absorbed into the skin without leaving a greasy residue.

Pros

  •  Paraben-free
  •  Gluten-free
  •  No artificial colors
  •  Cruelty-free
  •  Pump dispenser
  •  Non-GMO
  •  Plant-based

Cons

  •  Some might not like the scent.

8. Best Dye-Free:InstaNatural Vitamin C Moisturizer

InstaNatural Vitamin C Moisturizer is a drugstore fine line and wrinkle cream. It incorporates the benefits of nature-friendly ingredients like shea butter, sunflower oil, meadowfoam seed oil, mandarin orange peel oil, aloe vera, argan, safflower, avocado, jojoba, rosemary, grapefruit, hibiscus, green tea, soybean, matricia extract among others. This wrinkle cream doubles up as a facial moisturizer and also has vitamin C, niacinamide, hyaluronic acid and other anti-aging ingredients. This formulation helps in boosting collagen to produce new skin cells and fight the signs of aging, therefore restoring the youthfulness of the skin.

Pros

  • Paraben-free
  • SLS-free
  • Mineral oil-free
  • Dye-free
  • Cruelty-free
  • Organic ingredients

Cons

  • Some users might not like the smell of the product
  • The consistency of the product might be thinner than expected.

9. Best Hypoallergenic:Pond’s Rejuveness Anti-Wrinkle Cream

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Say bye to dry winter skin, wrinkles, fine lines, blemishes, dark spots, and other signs of aging with Pond’s Rejuveness Anti-Wrinkle Cream. This potent anti-aging formulation includes Alpha Hydroxy Acids (AHAs) and collagen that help in the production of new cells. This in turn, helps the skin to restore it’s natural youthfulness and aids in fighting the visible signs of aging, resulting in the minimization of their appearance. Feel younger and fresh as your hydrated skin radiates a soft glow with the regular use of this anti-wrinkle cream.

Pros

  • Paraben-free
  • Dermatologically tested
  • Hypoallergenic
  • Non-comedogenic

Cons

  • Some might find the smell of the product too strong

10. Best Fragrance-Free:CeraVe Skin Renewing Day Cream

CeraVe brings the Skin Renewing Day Cream that provides nourishment and moisturization to the skin. This gently formulated drugstore wrinkle day cream has encapsulated retinol and 3 essential ceramides that effectively help in reducing the appearance of wrinkles, fine lines, uneven skin tone, and other signs of aging. The protective layer of the skin is also restored, which is helpful to maintain a healthy, bright and smooth skin. Bring back the charm of your youthful skin and make it more supple with the regular usage of this anti-wrinkle day cream.

Pros

  • Paraben-free
  • Fragrance-free
  • Gentle formulation
  • Non-comedogenic
  • Dermatologically recommended

Cons

  • Some users might find the skin chalky and dry after using the product

11. Best For Dull Skin:DERMA E Anti-Wrinkle Renewal Cream

Make an eco-ethical choice by using the Derma E Anti-Wrinkle Renewal Cream. It is made with a host of natural ingredients like safflower seed oil, glycerin, avocado oil, sesame seed oil, sunflower seed oil, soybean oil, cedarwood essential oil, vitamin A, vitamin E and others. This formulation ensures that there is a visible improvement in the signs of aging like wrinkles, fine lines, uneven skin tone, etc. This cocktail of peptides also helps in minimizing dullness and roughness and works to restore the skin texture, elasticity, firmness and the overall youthful glow and radiance.

Pros

  • Paraben-free
  • Sulfate-free
  • Gluten-free
  • Mineral oil-free
  • Lanolin-free
  • Cruelty-free
  • Vegan

Cons

  • Some might find the product greasy and sticky on the skin

12. Best Colorant-Free:Olay Professional ProX Wrinkle Smoothing Cream

Fight the signs of aging like a pro with the Olay Professional ProX Wrinkle Smoothing Cream. With niacinamides, amino-peptides, glycerin and other potent anti-aging ingredients, this budget friendly wrinkle cream solves the root cause of anti-aging. It repairs the skin damage caused due to sun, slow renewal and dehydration. This gently formulated anti-wrinkle cream aids in the production of new skin cells, thereby restoring the youthfulness of the skin and making it look healthier and radiant as ever.

Pros

  • Paraben-free
  • Fragrance-free
  • Colorant-free
  • Dermatologically designed

Cons

  • Users with sensitive skin might develop allergic reactions

13. Best Elasticity Boosting :Onespring Pro Retinol Moisturizing Cream 

Minimize dryness and irritation with the Onespring Pro Retinol Moisturizing Cream. This retinol-based anti-wrinkle cream minimizes fine lines, wrinkles, and rough texture and evens out the skin tone. This moisturizing cream is infused with retinol, vitamin E, sodium hyaluronate, algae extract, and squalane. Additionally, the collagen and hyaluronic acid present in the cream aids in cell renewal and boost elasticity.

Pros

  •  Paraben-free
  •  Phthalate-free
  •  SLS-free
  •  SLES-free
  •  Cruelty-free

Cons

None

Aging is inevitable, but you can minimize the appearance of aging signs and combat the fine lines and wrinkles with the right skin care products. It is essential to provide extra attention to mature skin, and the best drugstore wrinkle creams will be of great help. These creams are loaded with powerful ingredients that nourish the skin and add a healthy glow to it. In addition, these creams can moisturize your skin and eliminate age-related imperfections. However, focus on paraben-free and sulfate-free creams as they are gentle on the skin. And steer clear of formulas that develop allergic reactions.

Why Trust StyleCraze?

Vaishnavi Kothuri, the author of this article, is a skin care enthusiast. Understanding the pain users feel in their quest for the perfect wrinkle cream, Sneha has taken extra care and gone through hundreds of reviews by users to pick the best wrinkle creams for her readers. This list offers a wide range of creams that reduce the appearance of wrinkles and keep your skin looking young and healthy on an affordable budget.

Frequently Asked Questions

What are the key ingredients to look for in a wrinkle cream?

The key ingredients to look for in a wrinkle cream are retinol, vitamin C, niacinamide, hyaluronic acid and peptides.

Does a wrinkle cream start working immediately and effectively?

In most cases, yes. It mostly depends on the age, skin type, and condition of the skin. To reap the maximum benefits, a wrinkle cream should be used regularly on a daily basis.

What is the best drugstore wrinkle cream for deep wrinkles around the mouth?

The InstaNatural Vitamin C Moisturizer is one of the best. It rejuvenates the skin while removing deep wrinkles from around the mouth. It contains anti-aging ingredients like vitamin C, niacinamide, and hyaluronic acid.

At what age should you start using drugstore wrinkle creams?

Start using drugstore wrinkle creams by the age of 30. It can delay the appearance of premature signs of aging while keeping your youthful glow intact.

Does anti-wrinkle cream tighten the skin?

Yes, anti-wrinkle creams tighten the skin. The skin-friendly formula in these creams comprising retinol, collagen, and hyaluronic acid promotes firmness.

Should you use anti wrinkle cream first or acne treatment?

The rule of the thumb is to use the lighter skin care product first. If we go by this, anti-wrinkle cream can be used before acne treatment.

How can I remove wrinkles from my face, at home?

You can massage your face with your fingers regularly to remove wrinkles. Make sure to use a skin-friendly, anti-wrinkle cream for visible results.

How often should you use an anti-wrinkle cream?

Use an anti-wrinkle cream twice or thrice a week for the best results.

When should I use an anti-wrinkle cream, day or night?

You can use an anti-wrinkle cream during the day and at night as well. Make sure that you are offering the cream enough time to get absorbed into your skin before applying other skin care products.

Recommended Articles:

Best Drugstore Anti-Aging Products, According To Reviews
Best Drugstore Wrinkle Fillers
Best Drugstore Retinol Creams For Wrinkle-Free Skin
Best Anti-Aging Skin Care Products To Turn Back The Clock
Best Drugstore Anti-Aging Eye Creams That Actually Work

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Vaishnavi is a techie-turned-content writer and a certified skin care coach. She did her postgraduation from Vignan Institute of Technology... more

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