13 Best Anti-Aging Supplements And Vitamins + Buying Guide (2023)

Aging is inevitable, but slowing the natural aging process has been a prime focus of scientific research for years now. While it is impossible to reverse the effects of aging, you can slow it down by taking anti-aging supplements.

While it is crucial to accept that anti-aging supplements are not magic pills that will make one look 20 when one is 40, these pills will help you age like fine wine by improving your overall skin health and protecting it from damage. However, it is always recommended that you consult a doctor before taking these pills. So keep reading to have a look at the best anti-aging supplements below!

Top 13 Anti-Aging Supplements That May Actually Work

1. Collagen

4.3

Image: Zeal Naturals

BUY ON AMAZON | $28.98

Buy on Walmart

Collagen is a protein that is naturally synthesized in the skin. It maintains the structure, stability, and strength of the skin layers which ensures proper skin hydration making it an excellent remedy for promoting cellular health. Your skin loses collagen with age, which weakens its structure and leads to dermal damage and the appearance of the signs of aging (1).

Hence, you need a collagen supplement to slow down the signs of aging and maintain the strength of your skin. It improves bone density and the healthy appearance of the skin. You can obtain collagen from animal sources (like bone broth, chicken skin, and fish oil) or consume an adequate intake of supplements, as suggested by the doctor.

Dosage Suggestion

A study found that a dosage of 2.5 grams per day to 10 grams per day of collagen hydrolysate could be beneficial for improving skin health (2). However, your doctor is the best person to guide you.

Supplement You May Try

Zeal Type 1 and Type 3 Collagen Peptides

Pros

• Promotes healthy skin, hair, and nail
• Supports bones and joints
• Improves skin smoothness
• Hydrates the skin
• Easy to swallow
• Keto-friendly
• Paleo-friendly
• Grass-fed
• GMO-free
• Gluten-free
• USDA approved

Cons

None

2. Nicotinamide Mononucleotide

4

Image: Perpetua.life

BUY ON AMAZON | $59

Nicotinamide Mononucleotide is an important nutrient that helps to suppress the visible signs of aging by reducing elastin loss from the skin. NMN rejuvenates blood vessels which help to improve body functions and increases energy level. It improves stem cells’ health, which reverses signs of aging and increases skin cell renewal.

NMN repairs DNA damage, which occurs as one gets older. This helps to improve brain health, fertility, skin glow, the hydration level of the skin, and its texture. NMN also helps to protect the skin from sun-related age damage, hyperpigmentation and the harmful effects of UV radiation.

Dosage Suggestion

You can consume 500 mg nicotinamide mononucleotide per day. It is advised to consult a physician for expert recommendation before starting the supplement to avoid any unwanted side effects.

Suggested Supplement You May Try

PERPETUA.LIFE Aeon Longevity Capsules

Pros

• Improves skin health
• Enhanced dermal thickness
• Prevents UV damage
• Repairs damaged cells
• Reduces aging signs
• Gives body strength
• Improves energy level
• Improves skin glow
• Long-lasting results
• No side-effects

Cons

None

Pro Tip

Older people must take their anti-aging supplements midday to speed up the digestion process because digestion slows down during sleep.

3. VitaMedica Anti-Aging Formula

5

The VitaMedica Anti-Aging Formula is a daily health supplement with a 4-in-1 combo of vitamins, minerals, omega-3s, and phytonutrients. It is made of 18 fruits, vegetables, spices, and herbs for a wholesome dosage to support various biological systems in the human body. The specialist-recommended formula contains vitamins A, C, and E to promote even skin tone and overall skin health, and organic flaxseed oil for supple skin and a natural glow. Phytonutrients improve internal photoprotection from harmful UVA and UVB rays and help reduce sun damage. Calcium, magnesium, and vitamin D work to improve general bone health. The B-complex, including biotin and pantothenic acid, offers thick, luscious hair and strong nails, while the omega-3s and antioxidants support aging health. This award-winning skin care formula comes in two morning and night dosages to improve energy levels during the day and aid in rest and relaxation at night.

Dosage Suggestion

The dosage includes a combination of AM and PM packets. The morning packet includes two tablets for energy support and a capsule of phyto-5 to be taken with breakfast or lunch. The evening packet includes two tablets for bone support and one capsule of organic flaxseed oil to be taken after dinner.

Pros

• Faster nail growth
• Improves sleep quality
• Improves skin elasticity
• Promotes skin hydration levels
• Softens the skin
• Gentle on the gastrointestinal system
• Soy-free
• Gluten-free
• Nut-free
• Vegan

Cons

• The pills can be hard to swallow for some.

4. NAD3+

4.2

Image: Hpn

BUY ON AMAZON | $35.95

NAD 3+ is important to boost metabolic levels of the human body and prevent premature aging. It helps repair damaged cells and restores the youthful glow of your skin. Optimum levels of NAD in the human body also help to ensure proper mitochondrial function to keep you healthy and youthful. It helps break down energy from cells and supply it to the body to repair damaged tissues. The nutrient plays an important role in protecting DNA from damage. This aids skin maintenance by protecting the skin cells from age-related damage and dullness.

Dosage Suggestion

It is recommended to take 312 mg of nicotinamide adenine dinucleotide per day. Do consult your doctor before starting the tablets for better professional advice.

Suggested Supplement You May Try

NAD3 Fountain Of Youth

Pros

• Reduces aging signs
• Helps cellular repair
• Reduce cell inflammation
• Boosts mitochondrial function
• Detoxifies your body
• Improves energy level
• Vegan
• Promotes healthy cholesterol

Cons

None

5. Vitamin E

4.5

Image: Nusapure

BUY ON AMAZON | $19.99

Buy on Walmart

The most common form of vitamin E that is available as a supplement is d-alpha-tocopherol. A study found that the oral intake of a combination of ascorbic acid (vitamin C) and d-alpha-tocopherol in human volunteers helped reduce skin damage caused by UV rays.

Also, taking natural vitamin E prevents collagen crosslinking and lipid peroxidation which supports skin rejuvenation thus preventing skin aging (6).

Dosage Suggestion

If you are taking synthetic alpha-tocopherol (through OTC supplements and fortified food), you need 50% more IU of the supplement to get the same amount of vitamin E that you will get from naturally available sources (7). Consult a doctor to determine the correct dosage for you.

Suggested Supplement You May Try

Nusa Pure Vitamin E

Pros

• All-natural ingredients
• Prevents Uv-induced damage
• Promotes healthy hair, skin, and eyes
• Supports healthy heart function
• Easy to swallow
• Value for money
• Non-greasy
• Non-GMO
• Gluten-free

Cons

• Not water soluble

6. Vitamin A

4.6

Image: Bronson

BUY ON AMAZON | $9.97

Buy on Walmart

There are two main types of vitamin A – retinoids and carotenoids. When you orally ingest vitamin A, your liver converts it to retinol. Once ingested, retinoids and carotenoids are distributed throughout your body.

Beta-carotene (a type of carotenoid) is a natural photoprotector. It prevents skin damage caused by UV rays (including photoaging and erythema) (6). Oral isotretinoin (a synthetic form of vitamin A) is said to improve skin thickness, skin tone, and elasticity, help with wrinkle reduction, and promote firmness(8).

Note: Do not take isotretinoin and vitamin A pills together. Taking isotretinoin with any other vitamin pills may cause toxicity.

Dosage Suggestion

The dosage for vitamin A (as a standalone supplement) has a wide range, depending on your age and health conditions (if any). Usually, the recommended dietary allowance for vitamin A for men (19+ years) is 900mcg RAE, and for healthy women (19+ years) is 700 mcg RAE. For pregnant women (19-50 years), it is 770 mcg RAE, and for lactating women (19-50 years), it is 1300 mcg RAE (9).

Consult your doctor for the right dosage, depending on the requirements of your body. If you are taking any medication for any health condition, vitamin A may interfere with it. Hence, do not self-medicate.

Suggested Supplement You May Try

Bronson Vitamin A

Pros

• Improves vision
• Improves the immunity system
• Maintains a healthy reproductive system
• Reduces acne
• Non-GMO

Cons

• Contains retinyl palmitate that can cause cancer.

7. Antioxidants

4.3

Image: Genius

BUY ON AMAZON | $89.99

Antioxidants can help treat early signs of aging and give new life to your skin. They conceal wrinkles, dark spots, and fine lines while treating discoloration and loss of tightness. They protect the skin from free radical damage, making your skin look younger, glowing, and plump, thus providing a radiant complexion.

Its age-defying antioxidants preserve the collagen content of the skin, and fight against oxidative stress, which helps to maintain its elasticity. They shield the skin against the harmful effects of sun exposure which can cause allergy, inflammation, and rashes and consequently make the skin look dull.

Some of the important antioxidants include vitamins A, B3, C and E along with resveratrol and green tea extract. They also protect the skin from harmful UV radiation and give it a brighter appearance.

Dosage Suggestion

Mix one scoop (7.1 grams) of the supplement with 12 ounces of cold water. It can be consumed daily to ensure sustained benefits. It is advised to consult a physician before starting the routine to give you professional and expert advice.

Suggested Supplement You May Try

Genius Glow Potion

Pros

• Gives glowing skin
• Treat skin imperfections
• Corrects aging signs
• Softens your skin
• Lightens dark spots
• Erases wrinkles, lines
• Safe for daily use
• Promotes cell growth

Cons

None

Remember

Do not exceed the recommended daily supplement intake time – at least one hour before a meal, two hours after any meal, or if you have a stomach upset from the zinc supplement, take it with a meal.

8. Curcumin

4.5

Image: Bioemblem

BUY ON AMAZON | $19.99

Buy on Walmart

Curcumin is a compound found in turmeric. It is responsible for the vibrant yellow color of the spice. Curcumin has anti-inflammatory effects and is effective in improving many dermatological conditions such as joint health, skin problems, and disturbed hormonal balance.

Studies suggest that curcumin supplements (both topical and oral) can improve various skin conditions caused by photoaging, like the signs of aging and skin damage caused by UV exposure (11).

Dosage Suggestion

As per the World Health Organization, the acceptable daily intake of curcuminoids (active compounds present in turmeric, including curcumin) as food additives is 0-3 mg/kg (12). However, your doctor is the best person to determine how much curcumin your body might need.

Suggested Supplement

BioEmblem Turmeric Curcumin

Pros

• Made with organic turmeric
• Promotes antioxidant benefits
• Improves joint and body pains
• Detoxifies the liver
• Relieves itchiness
• Affordable
• FDA-approved
• Non-GMO
• Vegan
• Gluten-free

Cons

• Might cause a sick stomach

9. Polyphenols

4.3

Image: Polyphenols

BUY ON AMAZON | $32.99

Buy on Walmart

Polyphenols are phytochemicals that naturally occur in many foods. These compounds have significant health benefits, including cell repair, photo-protective effects, and preventing the signs of aging.

Dietary polyphenols protect your skin and prevent a variety of skin issues (13). Consume dark chocolate, berries (grapes), fruits, soy, beans,and plant supplements to increase your intake of polyphenols.

Dosage Suggestion

Self-medicating is strictly not recommended in the case of polyphenol supplements, as unregulated intake may cause adverse health effects. Also, polyphenols tend to interact with medications, and it is strictly recommended to consult a doctor to know your dosage.

Suggested Supplement

Health Logics Green Tea Extract Supplement

Pros

• Supports liver detoxification
• Promotes a healthy cardiovascular system
• Burns the extra calories
• No artificial colors
• Preservative-free
• Gluten-free
• Yeast-free
• No added sugars

Cons

None

10. Apigenin

4.3

Image: Apigenin

BUY ON AMAZON | $16.95

Apigenin is a flavonoid. Your body gets apigenin mainly through fruits, vegetables, and herbs (such as chamomile). This compound promotes wound healing and tissue repair. It can promote collagen production, which is important for maintaining your skin and offering a youthful appearance (15).

Dosage Suggestion

Apigenin may be sedative in high quantities. Avoid taking these supplements without consulting a doctor.

Suggested Supplement

DORADO APIGENIN Maximum Strength

Pros

• Improves strength
• Improves sleep quality
• Reduces stress
• Non-GMO
• GMP certified
• Gluten-free
• Vegan
• Sugar-free
• Yeast-free

Cons

• Might slow down the MAOA activity

11. Vitamins

4.3

Image: Vita Medica

BUY ON AMAZON | $60

Premature aging is often caused due to stress, an unhealthy lifestyle and nutrient deficiency. Regular intake of vitamins keeps your body healthy, ensures a strong immune system and gives you a youthful glow.

Vitamins help to boost skin elasticity and keep it supple. They are a powerful source of anti-aging nutrients. With the right vitamins, you can protect your skin from the harmful effects of UV radiation and conceal visible signs of aging like wrinkles, fine lines etc. They also help to boost cell regeneration.

However, most vitamins are not naturally produced in our bodies and need to be consumed either by eating vitamin-rich foods or taking health supplements.

Dosage Suggestion

You can consume 510 micrograms of vitamin A, 6 mg of vitamin B2, 100 mg of vitamin C, and 8 micrograms of vitamin D along with 40 mg of vitamin E every day. However, one must consult the doctor for accurate suggestions before starting to use the multivitamin formula.

Suggested Supplement You May Try

VitaMedica Anti-Aging Formula

Pros

• Reduces aging signs
• Good for skin, nails
• Better energy and sleep
• Clinically tested
• Physician formulated
• Boosts energy levels

Cons

None

12. Fisetin

4.1

Image: Senolyfe

BUY ON AMAZON | $48.97

Buy on Walmart

This antioxidant is found in plants and is said to reduce inflammation, thereby improving the vitality of your cells.

In a study done on mice, researchers tested 10 flavonoids. Out of all, Fisetin has was the most senolytic, which means it can destroy the senescent or old cells and improve overall health. The researchers found that it extended the median and maximum lifespan of the mice (18).

Fisetin naturally occurs in onions, apples, and persimmons. However, you can also take supplements as prescribed by the doctor.

Dosage Suggestion

Since human trials on Fisetin are ongoing, it is still not clear if it will have the same effect on humans as mice. On average, the daily intake of flavonoids in the US is 1 gram per day (19). However, it may differ. Hence, it is better to consult a doctor before you take Fisetin supplements.

Suggested Supplement You May Try

Fisetin 500

Pros

• Promotes senolytic activity in cells
• Boosts antioxidant benefits
• Improves memory retention
• GMO-free
• Vegan
• Gluten-free
• GMP Certified

Cons

• Expensive

13. Nicotinamide Riboside

4.3

Image: Tru Niagen

BUY ON AMAZON | $119.95

Buy on Walmart

Nicotinamide riboside is a form of vitamin B3. Researchers have found that this vitamin is a neuroprotective agent. In other words, it protects your brain from toxins by improving the ratio of NAD+ and NADH. Your body needs these compounds to prevent DNA damage and improve overall health (20), (21).

Dosage Suggestion

The daily dosage allowance of nicotinamide riboside in adult men and women is 16 mg and 14 mg per day, respectively. A higher dosage of the supplement may cause cardiovascular risk. Consult your doctor to determine the correct dosage for you.

Suggested Supplement You May Try

TRU Niagen

Pros

• Improves muscles strength
• Maintains healthy heart and brain
• Repairs damaged cells
• Reduces stress
• Improves sleep quality

Cons

• Can adversely affect the glucose metabolism.
• Contains niagen that can cause cancer.

Do not try any supplements without consulting a doctor. Before buying any supplements, make sure you keep in mind the following things.

Tips To Find Safe Supplements

• Do a lot of research on the supplement you are considering. Check whether it has research-backed benefits or not.
• Ask your doctor. Inform them if you are taking any prescription medicine for any other health condition. Do not self-medicate as supplements can interact with medications and cause adverse reactions.
• Check for the brand. Supplements are unregulated, and the same supplement may have different combinations as per the brand. Some supplements may not contain all the ingredients mentioned in the label. Check the website of the brand if their supplement is tested and verified by any third-party agency regarding the ingredients on the label and the pills/powder/soft gels.

Why Trust StyleCraze?

We have curated this detailed list of best anti-aging supplements after thorough research. We went through numerous reviews and feedback on trusted online forums to help you pick the perfect supplements. The products listed in this article may improve overall skin health and protect it from damage.

Frequently Asked Questions

Is it ok to use anti-aging products in your 20s?

The skin starts aging from 25, and that is when you should start using anti-aging topical products. However, if it is a supplement, it is better to ask a doctor.

When is the best time to take collagen pills?

Check with your doctor. They can tell you whether your body lacks collagen or not and then determine the correct supplement.

Do anti-aging supplements work?

Yes. Anti-aging supplements reverse or slow down aging signs. They rejuvenate skin and improve its elasticity. They also prevent wrinkles and eliminate crepey skin.

What is the best supplement for younger-looking skin?

Collagen is the best supplement for younger-looking skin. It improves skin elasticity, adds moisture to the skin, eliminates wrinkles and fine lines, and retains the skin’s youthful glow.

How do I use anti-aging supplements?

Maintain a balanced diet and take anti-aging supplements to gain the best results. Follow the instructions on the product label while using the anti-aging supplements or do as your physician says.

How long do anti-aging supplements take to work?

Anti-aging supplements take at least three months to show effective results.

Was this article helpful?

The following two tabs change content below.

• Expert
• Author
• Editor
• Fact-checker

• Yolanda MooreMPAS, PA-C

  Yolanda Moore, MPAS, PA-C, is a physician assistant in Fresno, CA, with 15 years of experience. She currently practices at California Emergency Physicians and is a member of the California Academy of PAs and the American Med Spa Association.
  
  Yolanda Moore, MPAS, PA-C, is a physician assistant in Fresno, CA, with 15 years of experience. She currently practices at California Emergency Physicians and is a member of the California Academy of PAs and the American Med Spa Association.

Aditi NaskarAssociate Commerce Editor

 

Aditi Naskar has a postgraduate degree in English literature from Presidency University, Kolkata, a bachelor’s degree in education from WBUTTEPA, Kolkata, and a diploma in health and wellness. She is an associate commerce editor with 5 years of experience and specializes in reviewing fitness and health products. She has previously worked as a scriptwriter for an educational technology company and...more

Medha DebCommerce Editor

Medha Deb is a commerce editor with a master's degree in applied linguistics from the University of Hyderabad, which has allowed her to develop a deep understanding of language and its application in various contexts. She specializes in the areas of beauty, health, and wellness and is committed to ensuring that the content on the website is of the highest...more

Rajeshwari DasAssociate Commerce Editor

Rajeshwari is a dedicated fitness and lifestyle enthusiast, deeply committed to enhancing our readers’ well-being and vitality. She has a master’s degree in Journalism & Mass Communication from the University of Calcutta. Her unwavering passion for evaluating fitness and wellness products, whether it's workout gear or exercise machines, her discerning advice, and her enthusiastic guidance are guaranteed to elevate your...more