10 Best Serums For Microneedling

Recover quickly after a microneedling session with lightweight and soothing serums.

Medically reviewed by Patricia Gaile EspinosaPatricia Gaile Espinosa, MD
By Oyendrila KanjilalOyendrila Kanjilal, Certified Skin Care Coach  • 
All products recommended on StyleCraze are independently selected by our editorial team. If you make a purchase through any of these links, we may receive a commission. Learn more about our product selection process here.

Using a serum is highly recommended while undergoing microneedling therapy, a minimally invasive procedure. So, which is the best serum for microneedling? Before we go ahead, let us first understand what is this therapy all about and how it works? This cosmetic procedure involves rolling a needle-covered derma roller on the skin to stimulate collagen production and reduce fine lines, wrinkles, dark spots, and acne scars. This Collagen Induction Therapy (CIT) makes the skin firmer and smoother. But why using a serum is recommended? A serum serves as a buffer between the skin and the derma-roller. This article lists 10 amazing serums that make your life easy during a microneedling session. Read on!

Top PicksCheck Price
Best Plant-Based: TruSkin Vitamin C SerumPrice on Amazon
Best Hydrating: Cosmedica Pure Hyaluronic Acid SerumPrice on Amazon
Best Fast-Absorbing: L’Oreal Paris RevitaliftPrice on Amazon
Best Vegan: Mad Hippie Advanced Skin Care Vitamin C SerumPrice on Amazon
Best Dermatologist-Tested: Vichy Mineral 89 Skin Fortifying Daily BoosterPrice on Amazon
Best Non-Greasy: StackedSkincare HA Hydrating SerumPrice on Amazon
Best Fragrance-Free: Drunk Elephant T.L.C. Framboos Glycolic Night SerumPrice on Amazon
Best For Damaged Skin: The Ordinary Niacinamide 10% + Zinc 1%High Strength VitaminPrice on Amazon
Best Moisturizing: First Aid Beauty Ultra Repair Hydrating SerumPrice on Amazon
Best Lightweight: Kate Somerville Wrinkle WarriorPrice on Amazon

The 10 Best Serums For Microneedling

1. Best Plant-Based: TruSkin Vitamin C Serum

TruSkin Vitamin C Serum

The TruSkin Vitamin C Serum is an advanced antioxidant serum that targets the most common signs of aging, such as brightness, firmness, fine lines, wrinkles, dark spots, and sunspots. The serum has a plant-based formulation and is free of synthetic color additives and fragrances. It contains active botanicals and nutrients needed to revitalize aging skin and restore a youthful appearance, like aloe vera, MSM, botanical hyaluronic acid, witch hazel, and organic jojoba oil. The serum can be used both in the morning and at night. Watch this video for a thorough understanding of the product.


  • Reduces fine lines and dark spots
  • Improves skin tone
  • Plant-based formulation
  • Free of synthetic colors, additives, and fragrances
  • Cruelty-free


  • Might dry out the skin.

protip_icon Pro Tip
Apply this serum in small tapping motions with your fingertips. Do not rub it on the skin excessively and let the product get absorbed on its own.

Price at the time of publication: $38.99

2. Best Hydrating: Cosmedica Pure Hyaluronic Acid Serum

Cosmedica Pure Hyaluronic Acid Serum

The Cosmedica Pure Hyaluronic Serum is a natural and organic serum that improves skin texture and brightness with intense moisture and balance. It is a hydrating facial moisturizer with 100 percent pure hyaluronic acid serum formula. Dr. Patricia Gaile Espinosa, MD, Philippine Dermatological Society, says, “ Hyaluronic acid has the ability to retain water and is a good ingredient to moisturize the skin. It also regulates wound healing and inflammation”. The serum has anti-aging properties and diminishes the appearance of fine lines and wrinkles. Your skin will look visibly plumper, softer, and smoother after using the serum. It is gentle and effective and can be used on sensitive skin. This video will give you a better insight into the qualities of the product.


  • Contains 100% hyaluronic acid
  • Improves skin texture and brightness
  • Diminishes fine lines and wrinkles
  • Ideal for sensitive skin
  • Vegan
  • Paraben-free
  • Fragrance-free
  • Oil-free
  • Cruelty-free


  • None

protip_icon Quick Tip
Apply the serum on slightly damp skin and follow with a moisturizer immediately to seal in the hydration.

3. Best Fast-Absorbing: L’Oreal Paris Revitalift

L'Oreal Paris Revitalift

The L’Oreal Paris Revitalift is an intensive hydrating serum. It contains 1.5 % pure hyaluronic acid that moisturizes and makes your skin visibly plumped. It helps reduce wrinkles and fine lines to provide an even complexion. The serum provides instant relief from dryness, and the skin feels smooth and tight. It deeply hydrates and claims to give younger-looking skin within just one week of use. The serum is lightweight and fast-absorbing. It provides a sheer finish and can be used under makeup as a primer.


  • Moisturizes and plumps the skin
  • Helps reduce wrinkles and fine lines
  • Evens out the skin tone
  • Lightweight
  • Fast-absorbing
  • Can be used as a primer before makeup
  • Fragrance-free
  • Mineral oil-free
  • Dye-free
  • Does not clog pores
  • Paraben-free
  • Dermatologist-tested


  • Sticky texture
  • May cause an allergic reaction.
Price at the time of publication: $20.25

4. Best Vegan: Mad Hippie Advanced Skin Care Vitamin C Serum

Mad Hippie Advanced Skin Care Vitamin C Serum

The Mad Hippie Vitamin C Serum has a tightening, brightening, and smoothening effect on the skin. The harmonious blend of antioxidants evens out the skin tone and improves skin texture. It also helps in the recovery of sun-damaged skin. Vitamin C reduces the appearance of fine lines and wrinkles and protects the skin from photoaging. The vitamin E in the serum is an antioxidant that reduces the appearance of wrinkles and blemishes. Ferulic acid has a compounding antioxidant effect when combined with vitamins C and E. Hyaluronic acid plumps up the skin and reduces wrinkles. The konjac root in the serum softens and smoothens the skin. Other ingredients like grapefruit, chamomile extracts, and clary sage help exfoliate the skin, provide a protective shield, and tone the skin. Here’s a personal review video to help you get a better understanding of the product


  • Tightens, brightens, and smoothens the skin
  • Acts as a natural toner and astringent
  • Vegan
  • Cruelty-free
  • GMO-free


  • Not suitable for sensitive and oily skin.

protip_icon Pro Tip
Use a vitamin C-induced toner with this hyaluronic acid-based serum for extra hydration and plumping.

Price at the time of publication: $27.19

5. Best Dermatologist-Tested: Vichy Mineral 89 Skin Fortifying Daily Booster

Vichy Mineral 89 Skin Fortifying Daily Booster

The Vichy Mineral 89 Skin Fortifying Daily Booster moisturizes, hydrates, and plumps the skin. It contains natural origin hyaluronic acid that gives a dose of strength to the skin. It is a lightweight, fast-absorbing -formula that provides 24-hour hydration to all skin types. It strengthens and repairs skin barriers to reveal a luminous, healthy-looking glow. It contains Vichy mineralizing water with 15 essential minerals that reduce stress caused due to pollution. The serum is dermatologist-tested, non-greasy, and non-sticky. Watch this video for a thorough understanding of the product.


  • Dermatologist-tested
  • Fragrance-free
  • Allergy-free
  • Paraben-free
  • Alcohol-free
  • Suitable for all skin types, including sensitive skin
  • Non-greasy


  • May cause breakouts.
Price at the time of publication: $29.99

6. Best Non-Greasy: StackedSkincare HA Hydrating Serum

StackedSkincare HA Hydrating Serum

The Stacked Skincare HA Hydrating Serum is non-greasy and rich in hyaluronic acid. The serum deeply moisturizes your skin. It also controls oil and visibly plumps fine lines. The serum is fast-absorbing and acts hydrates the skin most effectively. It contains trehalose, lactic acid, and niacinamide that condition, brighten, and balance the oil levels in your skin. The serum has a soft, floral Balinese champaca fragrance.


  • Non-greasy
  • Lightweight
  • Ideal for all skin types
  • Controls oil
  • Softens skin
  • Plumps fine lines
  • Deeply moisturizes the skin


  • Expensive

7. Best Fragrance-Free: Drunk Elephant T.L.C. Framboos Glycolic Night Serum

Drunk Elephant T.L.C. Framboos Glycolic Night Serum

The Drunk Elephant Night Serum helps refine and resurface the skin to reveal a smoother and radiant-looking complexion. It enhances the performance of other products by clearing the way for maximum absorption. The serum resurfaces dull skin and gently lifts dead skin cells away. It delivers precise chemical exfoliation without harsh side effects like dryness or sensitization.


  • Helps refine and resurface the skin
  • Resurfaces dull skin
  • Gently lifts dead skin cells
  • Gives a clear, smooth, and even-looking complexion
  • Fragrance-free
  • Silicone-free
  • Cruelty-free


  • May cause breakouts.
Price at the time of publication: $62.0

8. Best For Damaged Skin: The Ordinary Niacinamide 10% + Zinc 1%High Strength Vitamin and Mineral Blemish Formula

The Ordinary Niacinamide 10% + Zinc 1%High Strength Vitamin and Mineral Blemish Formula

The Ordinary Niacinamide + Zinc Serum combats blemishes, congestion, and sebum overproduction. It has a lightweight, ultra-high concentration formula. It works to reduce the appearance of existing blemishes and prevents future breakouts. The serum contains niacinamide that boosts the skin’s immunity and improves moisture retention by strengthening the epidermal barrier. The serum also contains zinc that supports the skin structure by healing damaged skin and encourages the production of collagen and elastin.


  • Reduces the appearance of blemishes
  • Prevents future breakouts
  • Boosts skin’s immunity
  • Improves moisture retention
  • Heals damaged skin


  • NoneThick and sticky

9. Best Moisturizing: First Aid Beauty Ultra Repair Hydrating Serum

First Aid Beauty Ultra Repair Hydrating Serum

The First Aid Beauty Ultra Repair Hydrating Serum is a universal serum that gives the skin its daily dose of moisture. It makes the skin soft, smooth, and youthful-looking. The serum instantly infuses into the skin and provides essential hydration to help plump the skin and minimize the appearance of fine lines and wrinkles. The hyaluronic acid in the serum is a moisture-locking agent that helps hydrate and nourish the skin. The serum also contains colloidal oatmeal and aloe leaf juice to calm and soothe irritated skin. The peptides and collagen smooth the skin and reduce the appearance of fine lines and wrinkles. The serum has a water-based gel texture that is absorbed quickly into the skin. It is lightweight and perfect for use during the day and night.


  • Suitable for all skin types, including sensitive skin
  • Minimizes fine lines and wrinkles
  • Absorbed quickly into the skin
  • Non-comedogenic
  • Perfect for day and night use
  • Allergy-tested
  • Gluten-free
  • Oil-free
  • Soy-free
  • Nano-free


  • May cause allergic reactions.
Price at the time of publication: $19.0

10. Best Lightweight: Kate Somerville Wrinkle Warrior

Kate Somerville Wrinkle Warrior 2-In-1 Plumping Moisturizer Image: Kate Somerville

The Kate Somerville Wrinkle Warrior works as a serum and a plumping moisturizer as well as a primer. This lightweight serum combats concerns like dryness and signs of aging, giving you smooth and younger-looking skin in just 30 minutes. It improves skin firmness, smoothes crow’s feet, and visibly diminishes the appearance of fine lines and wrinkles. It has hyaluronic acid to deliver intense hydration and glucosamine to increase skin elasticity. It further has a blend of amino acids, activated sugar, and copper, clinically proven to target the wrinkles for a smooth and toned skin.


  • Lightweight
  • Fast-absorbing
  • Immediate results
  • 3-in-1 formula


  • None
Price at the time of publication: $98.0

How To Pick The Best Microneedling Serum For Your Skin

Hydrating and soothing serums are a great option both before and after a microneedling therapy session. They help maximize the overall benefits of the treatment. Let us take a look at some factors to consider before selecting a serum for microneedling.

1. Ingredients To Use

Your skin is highly sensitive after a microneedling treatment. So, it will need ingredients that help keep the barrier healthy while providing relief from irritation. Below are some ingredients you should keep an eye out for in a microneedling serum.

  • Hyaluronic acid

Hyaluronic acid is one of the most popular hydrating ingredients found in most serums and moisturizers. The microneedling process can maximize product absorption, so applying a hyaluronic acid serum will only make the benefits tenfold. Ensure that you get a serum with hyaluronic acid as the main ingredient without any preservatives or allergens.

  • Ceramides

Ceramides are the fatty acids found naturally on the stratum corneum (outermost layer of skin). They are essential for the skin to lock in moisture and keep the skin barrier healthy. Using a ceramide serum during microneedling will accelerate healing and prevent post-treatment tightness in the skin.

  • Peptides

Peptides are small chains of amino acids that naturally occur in the body and act as building blocks of collagen in the skin. They have incredible anti-aging, plumping, and skin-firming properties.

  • Epidermal Growth Factors (EGF)

EGF is a polypeptide with about 50 amino acids and is produced by the body to stimulate cell growth. They play a pivotal role in hydration, reducing the appearance of wrinkles, and preventing hyperpigmentation. You can apply EGF serum before and after microneedling.

2. Ingredients To Avoid

Microneedling can render your skin highly irritated and prone to sensitivity and there are certain ingredients that will only add to that sensitivity. Avoid active ingredients like alpha hydroxy acids (AHAs), beta hydroxy acids (BHAs), and retinoids..

3. Skin Type

If you have dry and sensitive skin, choose a deeply nourishing and replenishing cream with a hydrating face cleanser. For people with combination and oily skin, a gel-based moisturizer without silicones is ideal for locking in hydration.

4. Formula

The ideal formula for a microneedling serum offers gentle hydration and anti-inflammation benefits. However, ensure that the formulas are free of fragrances, chemicals, or allergens that may worsen your skin condition and cause potential irritation.

Infographic: Tips To Buy The Best Serum For Microneedling

Microneedling is a therapy for your skin that helps promote better skin. Using a serum alongside the treatment will increase its effectiveness. It works as a buffer and helps the device glide smoothly over the skin. It also helps the skin absorb the best of the serum and the therapy. But how do you choose the right serum? Check out the infographic below to understand the factors that make a good choice of serum for microneedling.

Tips To Buy The Best Serum For Microneedling

Illustration: StyleCraze Design Team

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Download Infographic in PDF version Download Infographic
Download Infographic in PDF version

If you have recently undergone microneedling therapy, you need serums that can help you recover faster and make your skin firm. These microneedling serums help promote collagen and reduce the signs of aging like wrinkles, dark spots, and fine lines. These products are eco-friendly and contain hyaluronic acid that helps in revitalizing your skin cells and restoring your glow. Dr. Patricia Gaile Espinosa, MD, Philippine Dermatological Society, says, “Avoid rubbing or scratching the skin for proper healing. Always wash hands before touching the face to avoid bacterial contamination while the wounds are fresh”. The serums on our list are cruelty-free, lightweight, and non-greasy. However, some products may cause breakouts and allergic reactions. So, choose the serums carefully and perform a patch test to avoid irritations.

Why Trust Stylecraze?

The author of this article, Oyendrila Kanjilal, is a certified skin care coach. She loves to experiment with new products and review them for her readers. She curated this list of the best serums for microneedling after conducting hours of research. These serums act as a buffer between the skin and the derma roller and help improve skin texture and diminish fine lines and wrinkles. The author has checked the ingredients of the serums and gone through multiple user review to shortlist the top-rated products for the list.

Frequently Asked Questions

Can I wash my face after microneedling?

Wait for 4 hours after a microneedling treatment to wash your face.

When can I exfoliate after microneedling?

Avoid exfoliating your face after a microneedling treatment. Your skin will be dry, swollen, and sensitive after the treatment, and further exfoliation might aggravate the sensitivity and swelling.

Do you put the serum on, before, or after microneedling?

You can apply the serum before or after microneedling as per your liking. However, do a patch test before applying it to your face.

How do I take care of my face after microneedling?

Use mild cleanser and clean water to gently cleanse your face for the next 24 hours post-microneedling. Pat the skin dry with a towel. Use hyaluronic acid post microneedling to keep your skin soothed and moisturized. Avoid makeup and direct sun exposure for 72 hours after microneedling.

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